UniProt P40818
Ubiquitin carboxyl-terminal hydrolase 8 (P40818)
Ubiquitin carboxyl-terminal hydrolase 8 (UniProt P40818), EC 3.4.19.12: 14 experimental structures on GenesisL1, 1 ligand bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P40818
- Protein
- Ubiquitin carboxyl-terminal hydrolase 8
- EC
- 3.4.19.12
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 21 · 2 records with a druggable one
Structures
14 records of P40818 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WHB | Solution structure of the Rhodanese-like domain in human ubiquitin specific protease 8 (UBP8) | solution nmr | A | — | — |
| 1WHB | Solution structure of the rhodanese-like domain in human ubiquitin specific protease 8 (UBP8) | solution nmr | A | — | — |
| 2A9U | Structure of the N-terminal domain of Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8) | x-ray diffraction | A, B | — | — |
| 2A9U | Structure of the N-terminal domain of human ubiquitin carboxyl-terminal hydrolase 8 (USP8) | x-ray diffraction | A, B | — | — |
| 2GFO | Structure of the Catalytic Domain of Human Ubiquitin Carboxyl-terminal Hydrolase 8 | x-ray diffraction | A | — | — |
| 2GFO | Structure of the catalytic domain of human ubiquitin carboxyl-terminal hydrolase 8 | x-ray diffraction | A | — | — |
| 2GWF | Structure of a USP8-NRDP1 complex | x-ray diffraction | A, C, E | — | — |
| 2GWF | Structure of a USP8-NRDP1 complex | x-ray diffraction | A, C, E | — | — |
| 3N3K | The catalytic domain of USP8 in complex with a USP8 specific inhibitor | x-ray diffraction | A | — | — |
| 3N3K | The catalytic domain of USP8 in complex with a USP8 specific inhibitor | x-ray diffraction | A | — | — |
| 6F09 | Binary complex of 14-3-3 zeta with ubiquitin specific protease 8 (USP8) pSer718 peptide | x-ray diffraction | A, B, C, D | — | 5 (best 0.74) |
| 6F09 | Binary complex of 14-3-3 zeta with ubiquitin specific protease 8 (USP8) PSER718 peptide | x-ray diffraction | A, B, C, D | — | — |
| 8XPN | The Crystal Structure of USP8 from Biortus. | x-ray diffraction | A, B, C | ZN | 16 (best 0.80) |
| P40818 | AlphaFold monomer V2.0 prediction for ubiquitin carboxyl-terminal hydrolase 8 (P40818) | — | — | — |
Ligands
- ZN · Zinc ion · in 1 record
Elsewhere
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