UniProt P40565
U2 snRNP component IST3 (P40565)
U2 snRNP component IST3 (UniProt P40565): 13 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P40565
- Protein
- U2 snRNP component IST3
- Experimental structures
- 13
- Predicted models
- 1
- Pockets
- 3 · 2 records with a druggable one
Structures
14 records of P40565 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2MKC | Cooperative Structure of the Heterotrimeric pre-mRNA Retention and Splicing Complex | solution nmr | A | — | — |
| 2MKC | Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex | solution nmr | A | — | — |
| 2MY2 | Snu17p-Bud13p structure intermediate during RES complex assembly | solution nmr | A | — | — |
| 2MY2 | SNU17P-BUD13P structure intermediate during res complex assembly | solution nmr | A | — | — |
| 2MY3 | Snu17p-Pml1p structure intermediate during RES complex assembly | solution nmr | A | — | — |
| 2MY3 | SNU17P-PML1P structure intermediate during res complex assembly | solution nmr | A | — | — |
| 4UQT | RRM-peptide structure in RES complex | solution nmr | A | — | — |
| 4UQT | Rrm-peptide structure in res complex | solution nmr | A | — | — |
| 5GM6 | Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution | electron microscopy | V | — | 1 (best 0.85) |
| 5LQW | yeast activated spliceosome | electron microscopy | J | — | — |
| 5LQW | Yeast activated spliceosome | electron microscopy | J | — | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | electron microscopy | X | — | 1 (best 0.80) |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström | electron microscopy | X | — | — |
| P40565 | AlphaFold monomer V2.0 prediction for U2 snrnp component IST3 (P40565) | predicted | A | — | 1 (best 0.24) |
Experiment against prediction
- 5ZWO chain X against the predicted model P40565: TM-score 0.94, RMSD 1.13 Å
- 5ZWO chain X against the predicted model P40565: TM-score 0.94, RMSD 1.13 Å
- 5GM6 chain V against the predicted model P40565: TM-score 0.94, RMSD 1.14 Å
- 4UQT chain A against the predicted model P40565: TM-score 0.90, RMSD 1.23 Å
- 4UQT chain A against the predicted model P40565: TM-score 0.90, RMSD 1.23 Å
- 2MKC chain A against the predicted model P40565: TM-score 0.83, RMSD 2.26 Å
- 2MKC chain A against the predicted model P40565: TM-score 0.83, RMSD 2.26 Å
- 2MY3 chain A against the predicted model P40565: TM-score 0.76, RMSD 2.09 Å
- 2MY3 chain A against the predicted model P40565: TM-score 0.76, RMSD 2.09 Å
- 2MY2 chain A against the predicted model P40565: TM-score 0.65, RMSD 2.22 Å
Elsewhere
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