UniProt P40427
Homeobox protein extradenticle (P40427)
Homeobox protein extradenticle (UniProt P40427): 17 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P40427
- Protein
- Homeobox protein extradenticle
- Experimental structures
- 17
- Predicted models
- 1
- Pockets
- 4 · 2 records with a druggable one
Structures
18 records of P40427 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1B8I | Structure of the homeotic UBX/EXD/DNA ternary complex | x-ray diffraction | B | — | — |
| 1B8I | Structure of the homeotic UBX/EXD/DNA ternary complex | x-ray diffraction | B | — | — |
| 2R5Y | Structure of Scr/Exd complex bound to a consensus Hox-Exd site | x-ray diffraction | B | — | — |
| 2R5Y | Structure of SCR/EXD complex bound to a consensus hox-exd site | x-ray diffraction | B | — | — |
| 2R5Z | Structure of Scr/Exd complex bound to a DNA sequence derived from the fkh gene | x-ray diffraction | B | — | — |
| 2R5Z | Structure of SCR/EXD complex bound to a DNA sequence derived from the fkh gene | x-ray diffraction | B | — | — |
| 4CYC | Crystal structure of a ubx-exd-DNA complex including the hexapeptide and ubda motifs | x-ray diffraction | B | — | — |
| 4CYC | Crystal structure of a ubx-exd-DNA complex including the hexapeptide and ubda motifs | x-ray diffraction | B | — | — |
| 4UUS | Crystal structure of a ubx-exd-DNA complex including the ubda motif | x-ray diffraction | B, F | — | — |
| 4UUS | Crystal structure of a ubx-exd-DNA complex including the ubda motif | x-ray diffraction | B, F | — | — |
| 5ZJQ | Structure of ABDB/EXD complex bound to a 'RED14' DNA sequence | x-ray diffraction | B | — | — |
| 5ZJR | Structure of AbdB/Exd complex bound to a 'Magenta14' DNA sequence | x-ray diffraction | B | — | 2 (best 0.72) |
| 5ZJR | Structure of ABDB/EXD complex bound to a 'MAGENTA14' DNA sequence | x-ray diffraction | B | — | — |
| 5ZJS | Structure of AbdB/Exd complex bound to a 'Blue14' DNA sequence | x-ray diffraction | B | — | 2 (best 0.72) |
| 5ZJS | Structure of ABDB/EXD complex bound to a 'BLUE14' DNA sequence | x-ray diffraction | B | — | — |
| 5ZJT | Structure of ABDB/EXD complex bound to a 'BLACK14' DNA sequence | x-ray diffraction | B | — | — |
| 7YB4 | Solution structure of homeodomain of EXTRADENTICLE | solution nmr | A | — | — |
| P40427 | AlphaFold monomer V2.0 prediction for homeobox protein extradenticle (P40427) | predicted | A | — | — |
Experiment against prediction
- 4CYC chain B against the predicted model P40427: TM-score 0.97, RMSD 0.52 Å
- 4CYC chain B against the predicted model P40427: TM-score 0.97, RMSD 0.52 Å
- 2R5Y chain B against the predicted model P40427: TM-score 0.96, RMSD 0.62 Å
- 2R5Y chain B against the predicted model P40427: TM-score 0.96, RMSD 0.62 Å
- 2R5Z chain B against the predicted model P40427: TM-score 0.96, RMSD 0.76 Å
- 2R5Z chain B against the predicted model P40427: TM-score 0.96, RMSD 0.76 Å
- 1B8I chain B against the predicted model P40427: TM-score 0.96, RMSD 0.61 Å
- 1B8I chain B against the predicted model P40427: TM-score 0.96, RMSD 0.61 Å
- 4UUS chain B against the predicted model P40427: TM-score 0.92, RMSD 0.92 Å
- 4UUS chain B against the predicted model P40427: TM-score 0.92, RMSD 0.92 Å
Elsewhere
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