UniProt P40356
Mediator of RNA polymerase II transcription subunit 3 (P40356)
Mediator of RNA polymerase II transcription subunit 3 (UniProt P40356): 3 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P40356
- Protein
- Mediator of RNA polymerase II transcription subunit 3
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 8 · 2 records with a druggable one
Structures
4 records of P40356 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UIK | Mediator-PIC Early (Tail A + Upstream DNA & Activator) | electron microscopy | c | — | 3 (best 0.80) |
| 7UIL | Mediator-PIC Early (Tail A/B Dimer) | electron microscopy | c, 2 | — | 5 (best 0.80) |
| 7UIO | Mediator-PIC Early (Composite Model) | electron microscopy | Ac, Bc | — | — |
| P40356 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 3 (P40356) | predicted | A | — | — |
Experiment against prediction
- 7UIO chain Ac against the predicted model P40356: TM-score 0.83, RMSD 2.04 Å
- 7UIO chain Bc against the predicted model P40356: TM-score 0.83, RMSD 2.04 Å
- 7UIL chain c against the predicted model P40356: TM-score 0.83, RMSD 2.04 Å
- 7UIL chain 2 against the predicted model P40356: TM-score 0.83, RMSD 2.04 Å
- 7UIK chain c against the predicted model P40356: TM-score 0.83, RMSD 2.04 Å
Elsewhere
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