UniProt P40040
Protein THO1 (P40040)
Protein THO1 (UniProt P40040): 9 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P40040
- Protein
- Protein THO1
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
10 records of P40040 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H1J | The SAP domain is a DNA-Binding Domain Capable of Binding S/MAR DNA | solution nmr | S | — | — |
| 1H1J | The sap domain is a DNA-binding domain capable of binding S/MAR DNA | solution nmr | S | — | — |
| 2WQG | SAP domain from Tho1: L31W (fluorophore) mutant | solution nmr | A | — | — |
| 2WQG | Sap domain from THO1: L31W (fluorophore) mutant | solution nmr | A | — | — |
| 4UZW | High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1 | solution nmr | A | — | — |
| 4UZW | High-resolution NMR structures of the domains of saccharomyces cerevisiae THO1 | solution nmr | A | — | — |
| 4UZX | High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1 | solution nmr | A | — | — |
| 4UZX | High-resolution NMR structures of the domains of saccharomyces cerevisiae THO1 | solution nmr | A | — | — |
| 8ENK | Crystal structure of UAP56 in complex with Tho1, the yeast homolog of human SARNP | x-ray diffraction | E | — | 2 (best 0.30) |
| P40040 | AlphaFold monomer V2.0 prediction for protein THO1 (P40040) | predicted | A | — | — |
Experiment against prediction
- 8ENK chain E against the predicted model P40040: TM-score 0.89, RMSD 1.04 Å
- 4UZX chain A against the predicted model P40040: TM-score 0.88, RMSD 1.34 Å
- 4UZX chain A against the predicted model P40040: TM-score 0.88, RMSD 1.34 Å
- 4UZW chain A against the predicted model P40040: TM-score 0.78, RMSD 1.49 Å
- 4UZW chain A against the predicted model P40040: TM-score 0.78, RMSD 1.49 Å
- 2WQG chain A against the predicted model P40040: TM-score 0.73, RMSD 2.32 Å
- 2WQG chain A against the predicted model P40040: TM-score 0.73, RMSD 2.32 Å
- 1H1J chain S against the predicted model P40040: TM-score 0.69, RMSD 1.91 Å
- 1H1J chain S against the predicted model P40040: TM-score 0.69, RMSD 1.91 Å
Elsewhere
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