UniProt P39075
Multidrug-efflux transporter 1 regulator (P39075)
Multidrug-efflux transporter 1 regulator (UniProt P39075): 33 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P39075
- Protein
- Multidrug-efflux transporter 1 regulator
- Experimental structures
- 33
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
34 records of P39075 in the MolNFT archive: 33 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1BOW | Multidrug-binding domain of transcription activator bmrr (apo form) | x-ray diffraction | A | — | — |
| 1BOW | Multidrug-binding domain of transcription activator bmrr (apo form) | x-ray diffraction | A | — | — |
| 1EXI | Crystal structure of transcription activator bmrr, from B. subtilis, bound to 21 base pair bmr… | x-ray diffraction | A | — | — |
| 1EXI | Crystal structure of transcription activator bmrr, from B. subtilis, bound to 21 base pair bmr… | x-ray diffraction | A | — | — |
| 1EXJ | Crystal structure of transcription activator bmrr, from B. subtilis, bound to 21 base pair bmr… | x-ray diffraction | A | — | — |
| 1EXJ | Crystal structure of transcription activator bmrr, from B. subtilis, bound to 21 base pair bmr… | x-ray diffraction | A | — | — |
| 1R8E | Crystal Structure of BmrR Bound to DNA at 2.4A Resolution | x-ray diffraction | A | — | — |
| 1R8E | Crystal structure of bmrr bound to DNA at 2.4A resolution | x-ray diffraction | A | — | — |
| 2BOW | Multidrug-binding domain of transcription activator bmrr in complex with a ligand… | x-ray diffraction | A | — | — |
| 2BOW | Multidrug-binding domain of transcription activator bmrr in complex with a ligand… | x-ray diffraction | A | — | — |
| 3D6Y | Crystal structure of R275E mutant of BMRR bound to DNA and berberine | x-ray diffraction | A | — | — |
| 3D6Y | Crystal structure of R275E mutant of bmrr bound to DNA and berberine | x-ray diffraction | A | — | — |
| 3D6Z | Crystal structure of R275E mutant of BMRR bound to DNA and rhodamine | x-ray diffraction | A | — | — |
| 3D6Z | Crystal structure of R275E mutant of bmrr bound to DNA and rhodamine | x-ray diffraction | A | — | — |
| 3D70 | Crystal structure of E253A mutant of BMRR bound to 22-bp oligonucleotide | x-ray diffraction | A | — | — |
| 3D70 | Crystal structure of E253A mutant of bmrr bound to 22-bp oligonucleotide | x-ray diffraction | A | — | — |
| 3D71 | Crystal structure of E253Q BMRR bound to 22 base pair promoter site | x-ray diffraction | A | — | — |
| 3D71 | Crystal structure of E253Q bmrr bound to 22 base pair promoter site | x-ray diffraction | A | — | — |
| 3IAO | Conformational plasticity of the coiled coil domain of BmrR is required for bmr promoter… | x-ray diffraction | A | — | — |
| 3IAO | Conformational plasticity of the coiled coil domain of bmrr is required for bmr promoter… | x-ray diffraction | A | — | — |
| 3Q1M | Crystal Structure of BmrR Dimer bound to DNA and the ligand 4-amino-quinaldine | x-ray diffraction | A | — | — |
| 3Q1M | Crystal structure of bmrr dimer bound to DNA and the ligand 4-amino- quinaldine | x-ray diffraction | A | — | — |
| 3Q2Y | Crystal Structure of BmrR bound to ethidium | x-ray diffraction | A | — | — |
| 3Q2Y | Crystal structure of bmrr bound to ethidium | x-ray diffraction | A | — | — |
| 3Q3D | Crystal structure of BmrR bound to puromycin | x-ray diffraction | A | — | — |
| 3Q3D | Crystal structure of bmrr bound to puromycin | x-ray diffraction | A | — | — |
| 3Q5P | Crystal structure of BmrR bound to Tetracycline | x-ray diffraction | A | — | — |
| 3Q5P | Crystal structure of bmrr bound to tetracycline | x-ray diffraction | A | — | — |
| 3Q5R | Crystal structure of BmrR bound to Kanamycin | x-ray diffraction | A | — | — |
| 3Q5R | Crystal structure of bmrr bound to kanamycin | x-ray diffraction | A | — | — |
| 3Q5S | Crystal structure of BmrR bound to Acetylcholine | x-ray diffraction | A | — | — |
| 3Q5S | Crystal structure of bmrr bound to acetylcholine | x-ray diffraction | A | — | — |
| 7CKQ | The cryo-EM structure of B. subtilis BmrR transcription activation complex | electron microscopy | G, I | P4P | 4 (best 0.77) |
| P39075 | AlphaFold monomer V2.0 prediction for multidrug-efflux transporter 1 regulator (P39075) | predicted | A | — | — |
Ligands
- P4P · Tetraphenylphosphonium · in 1 record
Experiment against prediction
- 3Q2Y chain A against the predicted model P39075: TM-score 0.98, RMSD 0.94 Å
- 3Q2Y chain A against the predicted model P39075: TM-score 0.98, RMSD 0.94 Å
- 3Q5P chain A against the predicted model P39075: TM-score 0.98, RMSD 0.95 Å
- 3Q5P chain A against the predicted model P39075: TM-score 0.98, RMSD 0.95 Å
- 3D71 chain A against the predicted model P39075: TM-score 0.98, RMSD 0.96 Å
- 3D71 chain A against the predicted model P39075: TM-score 0.98, RMSD 0.96 Å
- 3D70 chain A against the predicted model P39075: TM-score 0.98, RMSD 0.98 Å
- 3D70 chain A against the predicted model P39075: TM-score 0.98, RMSD 0.98 Å
- 3D6Z chain A against the predicted model P39075: TM-score 0.98, RMSD 1.02 Å
- 3D6Z chain A against the predicted model P39075: TM-score 0.98, RMSD 1.02 Å
Elsewhere
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