UniProt P38920
DNA mismatch repair protein MLH1 (P38920)
DNA mismatch repair protein MLH1 (UniProt P38920): 11 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P38920
- Protein
- DNA mismatch repair protein MLH1
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 0 records with a druggable one
Structures
12 records of P38920 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4E4W | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1)… | x-ray diffraction | A | — | — |
| 4E4W | Structure of the C-terminal domain of the saccharomyces cerevisiae mutl alpha (MLH1/PMS1)… | x-ray diffraction | A | — | — |
| 4FMN | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1)… | x-ray diffraction | A | — | — |
| 4FMN | Structure of the C-terminal domain of the saccharomyces cerevisiae mutl alpha (MLH1/PMS1)… | x-ray diffraction | A | — | — |
| 4FMO | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1)… | x-ray diffraction | A | — | — |
| 4FMO | Structure of the C-terminal domain of the saccharomyces cerevisiae mutl alpha (MLH1/PMS1)… | x-ray diffraction | A | — | — |
| 6RMN | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | A | ZN | 4 (best 0.45) |
| 6RMN | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | A | ZN | — |
| 6SHX | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | A | ZN | — |
| 6SNS | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | A | ZN | — |
| 6SNV | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | A, D | ZN | — |
| P38920 | AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MLH1 (P38920) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 5 records
Experiment against prediction
- 4FMO chain A against the predicted model P38920: TM-score 0.96, RMSD 1.19 Å
- 4FMO chain A against the predicted model P38920: TM-score 0.96, RMSD 1.19 Å
- 4FMN chain A against the predicted model P38920: TM-score 0.96, RMSD 1.21 Å
- 4FMN chain A against the predicted model P38920: TM-score 0.96, RMSD 1.21 Å
- 4E4W chain A against the predicted model P38920: TM-score 0.96, RMSD 1.28 Å
- 4E4W chain A against the predicted model P38920: TM-score 0.96, RMSD 1.28 Å
- 6SHX chain A against the predicted model P38920: TM-score 0.96, RMSD 1.67 Å
- 6RMN chain A against the predicted model P38920: TM-score 0.95, RMSD 1.43 Å
- 6RMN chain A against the predicted model P38920: TM-score 0.95, RMSD 1.43 Å
- 6SNS chain A against the predicted model P38920: TM-score 0.95, RMSD 1.46 Å
Elsewhere
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