UniProt P38313
Inner kinetochore subunit AME1 (P38313)
Inner kinetochore subunit AME1 (UniProt P38313): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P38313
- Protein
- Inner kinetochore subunit AME1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 13 · 2 records with a druggable one
Structures
9 records of P38313 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NUW | Yeast CTF19 complex | electron microscopy | I | — | — |
| 6QLD | Structure of inner kinetochore CCAN-Cenp-A complex | electron microscopy | U | — | — |
| 6QLD | Structure of inner kinetochore ccan-cenp-a complex | electron microscopy | U | — | — |
| 6QLE | Structure of inner kinetochore ccan complex | electron microscopy | U | — | — |
| 6QLF | Structure of inner kinetochore ccan complex with MASK1 | electron microscopy | U | — | — |
| 8OVX | Cryo-EM structure of yeast CENP-OPQU+ bound to the CENP-A N-terminus | electron microscopy | U | — | 5 (best 0.74) |
| 8OW1 | Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | electron microscopy | U, UU | — | 8 (best 0.85) |
| 8T0P | Structure of Cse4 bound to Ame1 and Okp1 | x-ray diffraction | B | SO4 | — |
| P38313 | AlphaFold monomer V2.0 prediction for inner kinetochore subunit AME1 (P38313) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 8OVX chain U against the predicted model P38313: TM-score 0.84, RMSD 1.48 Å
- 8T0P chain B against the predicted model P38313: TM-score 0.77, RMSD 2.73 Å
- 8OW1 chain UU against the predicted model P38313: TM-score 0.71, RMSD 3.79 Å
- 8OW1 chain U against the predicted model P38313: TM-score 0.70, RMSD 3.91 Å
- 6QLF chain U against the predicted model P38313: TM-score 0.70, RMSD 3.77 Å
- 6QLE chain U against the predicted model P38313: TM-score 0.70, RMSD 3.83 Å
- 6QLD chain U against the predicted model P38313: TM-score 0.68, RMSD 3.84 Å
- 6QLD chain U against the predicted model P38313: TM-score 0.68, RMSD 3.84 Å
- 6NUW chain I against the predicted model P38313: TM-score 0.67, RMSD 3.62 Å
Elsewhere
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