UniProt P38121
DNA polymerase alpha subunit B (P38121)
DNA polymerase alpha subunit B (UniProt P38121): 5 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P38121
- Protein
- DNA polymerase alpha subunit B
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 2 · 2 records with a druggable one
Structures
6 records of P38121 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3FLO | Crystal structure of the carboxyl-terminal domain of yeast DNA polymerase alpha in complex with its… | x-ray diffraction | A, C, E, G | — | — |
| 3FLO | Crystal structure of the carboxyl-terminal domain of yeast DNA polymerase alpha in complex with its… | x-ray diffraction | A, C, E, G | — | — |
| 8B9A | S. cerevisiae replisome + Ctf4, bound by pol alpha primase. Complex engaged with a fork DNA… | electron microscopy | B | — | 1 (best 0.79) |
| 8B9B | S. cerevisiae replisome + Ctf4, bound by pol alpha. Complex engaged with a fork DNA substrate… | electron microscopy | B | — | — |
| 8B9C | S. cerevisiae pol alpha - replisome complex | electron microscopy | B | — | 1 (best 0.78) |
| P38121 | AlphaFold monomer V2.0 prediction for DNA polymerase alpha subunit B (P38121) | predicted | A | — | — |
Experiment against prediction
- 3FLO chain C against the predicted model P38121: TM-score 1.00, RMSD 0.29 Å
- 3FLO chain C against the predicted model P38121: TM-score 1.00, RMSD 0.29 Å
- 3FLO chain E against the predicted model P38121: TM-score 1.00, RMSD 0.29 Å
- 3FLO chain E against the predicted model P38121: TM-score 1.00, RMSD 0.29 Å
- 3FLO chain A against the predicted model P38121: TM-score 1.00, RMSD 0.30 Å
- 3FLO chain A against the predicted model P38121: TM-score 1.00, RMSD 0.30 Å
- 3FLO chain G against the predicted model P38121: TM-score 1.00, RMSD 0.30 Å
- 3FLO chain G against the predicted model P38121: TM-score 1.00, RMSD 0.30 Å
- 8B9A chain B against the predicted model P38121: TM-score 0.86, RMSD 0.56 Å
- 8B9B chain B against the predicted model P38121: TM-score 0.86, RMSD 0.56 Å
Elsewhere
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