UniProt P37634
Ribosomal RNA large subunit methyltransferase J (P37634)
Ribosomal RNA large subunit methyltransferase J (UniProt P37634), EC 2.1.1.266: 11 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, druggability and experiment against…
- UniProt
- P37634
- Protein
- Ribosomal RNA large subunit methyltransferase J
- EC
- 2.1.1.266
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 14 · 3 records with a druggable one
Structures
12 records of P37634 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4BLU | Crystal structure of Escherichia coli 23S rRNA (A2030-N6)- methyltransferase RlmJ | x-ray diffraction | A, B | — | — |
| 4BLU | Crystal structure of escherichia COLI 23S rRNA (A2030-N6)- methyltransferase rlmj | x-ray diffraction | A, B | — | — |
| 4BLV | Crystal structure of Escherichia coli 23S rRNA (A2030-N6)- methyltransferase RlmJ in complex with… | x-ray diffraction | A, B | — | — |
| 4BLV | Crystal structure of escherichia COLI 23S rRNA (A2030-N6)- methyltransferase rlmj in complex with… | x-ray diffraction | A, B | — | — |
| 4BLW | Crystal structure of Escherichia coli 23S rRNA (A2030-N6)- methyltransferase RlmJ in complex with… | x-ray diffraction | A, B | — | — |
| 4BLW | Crystal structure of escherichia COLI 23S rRNA (A2030-N6)- methyltransferase rlmj in complex with… | x-ray diffraction | A, B | — | — |
| 7P8Q | Structure of E.coli RlmJ in complex with an RNA conjugate (GA-SAM) | x-ray diffraction | A | 6D6 | 3 (best 0.57) |
| 7P8Q | Structure of E.COLI rlmj in complex with an RNA conjugate (ga-SAM) | x-ray diffraction | A | 6D6 | — |
| 7P9I | Structure of E.coli RlmJ in complex with an RNA conjugate (GAA-SAM) | x-ray diffraction | A, B | 6D6 | 7 (best 0.75) |
| 7P9I | Structure of E.COLI rlmj in complex with an RNA conjugate (gaa-SAM) | x-ray diffraction | A, B | 6D6 | — |
| 7P9O | Structure of E.COLI rlmj in complex with a SAM analogue (ca) | x-ray diffraction | A | — | — |
| P37634 | AlphaFold monomer V2.0 prediction for ribosomal RNA large subunit methyltransferase J (P37634) | predicted | A | — | 4 (best 0.52) |
Ligands
- 6D6 · 5'-{[(3S)-3-amino-3-carboxypropyl](3-aminopropyl) amino}-5'-deoxyadenosine · in 4 records
Experiment against prediction
- 4BLW chain A against the predicted model P37634: TM-score 0.99, RMSD 0.44 Å
- 4BLW chain A against the predicted model P37634: TM-score 0.99, RMSD 0.44 Å
- 4BLV chain A against the predicted model P37634: TM-score 0.99, RMSD 0.52 Å
- 4BLV chain A against the predicted model P37634: TM-score 0.99, RMSD 0.52 Å
- 4BLW chain B against the predicted model P37634: TM-score 0.99, RMSD 0.43 Å
- 4BLW chain B against the predicted model P37634: TM-score 0.99, RMSD 0.43 Å
- 7P9I chain A against the predicted model P37634: TM-score 0.98, RMSD 0.87 Å
- 7P9I chain A against the predicted model P37634: TM-score 0.98, RMSD 0.87 Å
- 7P9I chain B against the predicted model P37634: TM-score 0.98, RMSD 0.96 Å
- 7P9I chain B against the predicted model P37634: TM-score 0.98, RMSD 0.96 Å
Elsewhere
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