UniProt P37088
Amiloride-sensitive sodium channel subunit alpha (P37088)
Amiloride-sensitive sodium channel subunit alpha (UniProt P37088): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P37088
- Protein
- Amiloride-sensitive sodium channel subunit alpha
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 2 records with a druggable one
Structures
5 records of P37088 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2M3O | Structure and dynamics of a human Nedd4 WW domain-ENaC complex | solution nmr | P | — | — |
| 2M3O | Structure and dynamics of a human NEDD4 ww domain-ENAC complex | solution nmr | P | — | — |
| 6WTH | Full-length human ENaC ECD | electron microscopy | A | NA, NAG | 9 (best 0.90) |
| 6WTH | Full-length human ENAC ecd | electron microscopy | A | NA, NAG | — |
| P37088 | AlphaFold monomer V2.0 prediction for amiloride-sensitive sodium channel subunit alpha (P37088) | predicted | A | — | 11 (best 0.69) |
Ligands
Experiment against prediction
- 6WTH chain A against the predicted model P37088: TM-score 0.98, RMSD 0.99 Å
- 6WTH chain A against the predicted model P37088: TM-score 0.98, RMSD 0.99 Å
- 2M3O chain P against the predicted model P37088: TM-score 0.53, RMSD 1.85 Å
- 2M3O chain P against the predicted model P37088: TM-score 0.53, RMSD 1.85 Å
Elsewhere
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