UniProt P36675
Alternative ribosome-rescue factor A (P36675)
Alternative ribosome-rescue factor A (UniProt P36675): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P36675
- Protein
- Alternative ribosome-rescue factor A
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 16 · 6 records with a druggable one
Structures
11 records of P36675 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5MDV | Structure of ArfA and RF2 bound to the 70S ribosome (accommodated state) | electron microscopy | 6 | — | — |
| 5MDW | Structure of ArfA(A18T) and RF2 bound to the 70S ribosome (pre-accommodated state) | electron microscopy | 6 | MG | 3 (best 0.85) |
| 5MDY | Structure of ArfA and TtRF2 bound to the 70S ribosome (pre-accommodated state) | electron microscopy | 6 | — | — |
| 5MGP | Structural basis for ArfA-RF2 mediated translation termination on stop-codon lacking mRNAs | electron microscopy | w | — | 1 (best 0.86) |
| 5U4I | Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome | electron microscopy | w | — | — |
| 5U4J | Structural Basis of Co-translational Quality Control by ArfA and RF2 Bound to Ribosome | electron microscopy | w | — | 7 (best 0.86) |
| 5U4J | Structural basis of co-translational quality control by arfa and RF2 bound to ribosome | electron microscopy | w | — | — |
| 5U9F | 3.2 A cryo-EM ArfA-RF2 ribosome rescue complex (Structure II) | electron microscopy | Y | — | 1 (best 0.83) |
| 5U9G | 3.2 A cryo-EM ArfA-RF2 ribosome rescue complex (Structure I) | electron microscopy | Y | — | 1 (best 0.82) |
| 6C4I | Conformation of methylated GGQ in the peptidyl transferase center during translation termination | electron microscopy | w | — | 3 (best 0.85) |
| P36675 | AlphaFold monomer V2.0 prediction for alternative ribosome-rescue factor a (P36675) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 1 record
Experiment against prediction
- 6C4I chain w against the predicted model P36675: TM-score 0.93, RMSD 0.58 Å
- 5U4J chain w against the predicted model P36675: TM-score 0.93, RMSD 0.64 Å
- 5U4J chain w against the predicted model P36675: TM-score 0.93, RMSD 0.64 Å
- 5MDV chain 6 against the predicted model P36675: TM-score 0.92, RMSD 0.65 Å
- 5U4I chain w against the predicted model P36675: TM-score 0.91, RMSD 0.75 Å
- 5MGP chain w against the predicted model P36675: TM-score 0.90, RMSD 0.78 Å
- 5U9F chain Y against the predicted model P36675: TM-score 0.89, RMSD 0.92 Å
- 5U9G chain Y against the predicted model P36675: TM-score 0.70, RMSD 1.10 Å
- 5MDY chain 6 against the predicted model P36675: TM-score 0.67, RMSD 1.10 Å
- 5MDW chain 6 against the predicted model P36675: TM-score 0.67, RMSD 1.13 Å
Elsewhere
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