UniProt P35680
Hepatocyte nuclear factor 1-beta (P35680)
Hepatocyte nuclear factor 1-beta (UniProt P35680): 4 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35680
- Protein
- Hepatocyte nuclear factor 1-beta
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
5 records of P35680 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DA6 | Solution structure of the homeobox domain of Hepatocyte nuclear factor 1-beta (HNF-1beta) | solution nmr | A | — | — |
| 2DA6 | Solution structure of the homeobox domain of hepatocyte nuclear factor 1-beta (hnf-1BETA) | solution nmr | A | — | — |
| 2H8R | Hepatocyte Nuclear Factor 1b bound to DNA: MODY5 Gene Product | x-ray diffraction | A, B | — | — |
| 2H8R | Hepatocyte nuclear factor 1B bound to DNA: MODY5 gene product | x-ray diffraction | A, B | — | — |
| P35680 | AlphaFold monomer V2.0 prediction for hepatocyte nuclear factor 1-beta (P35680) | predicted | A | — | 1 (best 0.50) |
Experiment against prediction
- 2H8R chain A against the predicted model P35680: TM-score 0.97, RMSD 0.92 Å
- 2H8R chain A against the predicted model P35680: TM-score 0.97, RMSD 0.92 Å
- 2H8R chain B against the predicted model P35680: TM-score 0.97, RMSD 0.92 Å
- 2H8R chain B against the predicted model P35680: TM-score 0.97, RMSD 0.92 Å
- 2DA6 chain A against the predicted model P35680: TM-score 0.76, RMSD 2.88 Å
- 2DA6 chain A against the predicted model P35680: TM-score 0.76, RMSD 2.88 Å
Elsewhere
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