UniProt P35637
RNA-binding protein FUS (P35637)
RNA-binding protein FUS (UniProt P35637): 26 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35637
- Protein
- RNA-binding protein FUS
- Experimental structures
- 26
- Predicted models
- 1
- Ligands
- 2
Structures
27 records of P35637 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LA6 | Solution NMR Structure of RRM domain of RNA-binding protein FUS from homo sapiens, Northeast… | solution nmr | A | — | — |
| 2LA6 | Solution NMR structure of rrm domain of RNA-binding protein fus from homo sapiens, northeast… | solution nmr | A | — | — |
| 2LCW | solution structure of FUS/TLS RRM domain | solution nmr | A | — | — |
| 2LCW | Solution structure of FUS/TLS rrm domain | solution nmr | A | — | — |
| 4FDD | Crystal structure of KAP beta2-PY-NLS | x-ray diffraction | B | — | — |
| 4FDD | Crystal structure of kap BETA2-py-nls | x-ray diffraction | B | — | — |
| 5W3N | Molecular structure of FUS low sequence complexity domain protein fibrils | solid-state nmr | A, B, C, D, E, F, G, H, I | — | — |
| 5W3N | Molecular structure of fus low sequence complexity domain protein fibrils | solid-state nmr | A, B, C, D, E, F, G, H, I | — | — |
| 5XRR | Crystal structure of fus (54-59) syssyg | x-ray diffraction | A | ZN | — |
| 5XSG | Ultrahigh resolution structure of fus (37-42) sysgys determined by microed | electron crystallography | A | — | — |
| 5YVG | Crystal structure of Karyopherin beta2 in complex with FUS(full length) | x-ray diffraction | X, Y | — | — |
| 5YVG | Crystal structure of karyopherin BETA2 in complex with FUS(FULL length) | x-ray diffraction | X, Y | — | — |
| 5YVH | Crystal structure of karyopherin BETA2 in complex with FUS(371-526) | x-ray diffraction | B | — | — |
| 5YVI | Crystal structure of karyopherin BETA2 in complex with FUS(456-526) | x-ray diffraction | B | — | — |
| 6BZP | Stggyg from low-complexity domain of fus, residues 77-82 | electron crystallography | A, B | TOE | — |
| 6G99 | Solution structure of fus-znf bound to uggug | solution nmr | B | ZN | — |
| 6GBM | Solution structure of fus-rrm bound to stem-loop RNA | solution nmr | B | — | — |
| 6KJ1 | 200KV microed structure of fus (37-42) sysgys solved from merged datasets at 0.65 a | electron crystallography | A | — | — |
| 6KJ2 | 200kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.67 A | electron crystallography | A | — | — |
| 6KJ2 | 200KV microed structure of fus (37-42) sysgys solved from single crystal at 0.67 a | electron crystallography | A | — | — |
| 6KJ3 | 120KV microed structure of fus (37-42) sysgys solved from merged datasets at 0.60 a | electron crystallography | A | — | — |
| 6KJ4 | 120KV microed structure of fus (37-42) sysgys solved from single crystal at 0.65 a | electron crystallography | A | — | — |
| 6SNJ | Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snrna stem loop III | solution nmr | A | — | — |
| 6XFM | Molecular structure of the core of amyloid-like fibrils formed by residues 111-214 of fus | electron microscopy | 1, 2, 3, 4, 5, 6, 7, 8 | — | — |
| 7CYL | Crystal structure of karyopherin-BETA2 in complex with fus py- NLS(P525L) | x-ray diffraction | B | — | — |
| 7VQQ | Cryo-EM structure of amyloid fibril formed by fus low complexity domain | electron microscopy | A, B, C | — | — |
| P35637 | AlphaFold monomer V2.0 prediction for RNA-binding protein fus (P35637) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6GBM chain B against the predicted model P35637: TM-score 0.90, RMSD 1.75 Å
- 2LA6 chain A against the predicted model P35637: TM-score 0.89, RMSD 1.72 Å
- 2LA6 chain A against the predicted model P35637: TM-score 0.89, RMSD 1.72 Å
- 5XRR chain A against the predicted model P35637: TM-score 0.81, RMSD 0.25 Å
- 2LCW chain A against the predicted model P35637: TM-score 0.75, RMSD 2.42 Å
- 2LCW chain A against the predicted model P35637: TM-score 0.75, RMSD 2.42 Å
- 6SNJ chain A against the predicted model P35637: TM-score 0.72, RMSD 2.26 Å
- 6G99 chain B against the predicted model P35637: TM-score 0.71, RMSD 2.06 Å
- 6BZP chain B against the predicted model P35637: TM-score 0.55, RMSD 0.65 Å
- 5YVI chain B against the predicted model P35637: TM-score 0.54, RMSD 1.17 Å
Elsewhere
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