UniProt P35613
Isoform 2 of Basigin (P35613)
Isoform 2 of Basigin (UniProt P35613): 19 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35613
- Protein
- Isoform 2 of Basigin
- Experimental structures
- 19
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 11 · 2 records with a druggable one
Structures
20 records of P35613 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3QQN | The retinal specific CD147 Ig0 domain: from molecular structure to biological activity | x-ray diffraction | A, B | — | — |
| 3QQN | The retinal specific CD147 IG0 domain: from molecular structure to biological activity | x-ray diffraction | A, B | — | — |
| 3QR2 | Wild type CD147 Ig0 domain | x-ray diffraction | A, B | — | — |
| 3QR2 | Wild type CD147 IG0 domain | x-ray diffraction | A, B | — | — |
| 4U0Q | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to basigin | x-ray diffraction | B, D | — | — |
| 4U0Q | Plasmodium falciparum reticulocyte-binding protein homologue 5 (PFRH5) bound to basigin | x-ray diffraction | B, D | — | — |
| 5X0T | Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody 6H8 | x-ray diffraction | E, F | — | 2 (best 0.73) |
| 5X0T | Crystal structure of CD147 C2 domain in complex with Fab of its monoclonal antibody 6H8 | x-ray diffraction | E, F | — | — |
| 5XF0 | Solution structure of the IgI domain of CD147 | solution nmr | A | — | — |
| 5XF0 | Solution structure of the igi domain of CD147 | solution nmr | A | — | — |
| 6LYY | Cryo-EM structure of the human MCT1/BASIGIN-2 complex in the presence of anti-cancer drug candidate… | electron microscopy | B | — | — |
| 6LZ0 | Cryo-EM structure of human MCT1 in complex with Basigin-2 in the presence of lactate | electron microscopy | B | — | — |
| 6LZ0 | Cryo-EM structure of human MCT1 in complex with basigin-2 in the presence of lactate | electron microscopy | B | — | — |
| 7CKO | Cryo-EM structure of the human MCT1/BASIGIN-2 complex in the presence of anti-cancer drug candidate… | electron microscopy | B | — | — |
| 7DA5 | Cryo-EM structure of the human MCT1 D309N mutant in complex with basigin-2 in the inward-open… | electron microscopy | B | — | — |
| 7DAA | Crystal structure of basigin complexed with anti-basigin Fab fragment | x-ray diffraction | A | CD | — |
| 7DCE | Cryo-EM structure of human XKR8-basigin complex bound to Fab fragment | electron microscopy | B | — | — |
| 7XY8 | Crystal structure of antibody Fab fragment in complex with CD147(EMMPIRIN) | x-ray diffraction | A, B | — | 7 (best 0.76) |
| 8XEJ | Cryo-EM structure of human XKR8-basigin complex in lipid nanodisc | electron microscopy | B | — | 2 (best 0.46) |
| P35613 | AlphaFold monomer V2.0 prediction for basigin (P35613) | predicted | A | — | — |
Ligands
- CD · Cadmium ion · in 1 record
Experiment against prediction
- 7DAA chain A against the predicted model P35613: TM-score 0.98, RMSD 0.53 Å
- 7XY8 chain B against the predicted model P35613: TM-score 0.97, RMSD 0.65 Å
- 5X0T chain F against the predicted model P35613: TM-score 0.97, RMSD 0.59 Å
- 5X0T chain F against the predicted model P35613: TM-score 0.97, RMSD 0.59 Å
- 5X0T chain E against the predicted model P35613: TM-score 0.97, RMSD 0.59 Å
- 5X0T chain E against the predicted model P35613: TM-score 0.97, RMSD 0.59 Å
- 3QR2 chain A against the predicted model P35613: TM-score 0.96, RMSD 0.92 Å
- 3QR2 chain A against the predicted model P35613: TM-score 0.96, RMSD 0.92 Å
- 3QQN chain A against the predicted model P35613: TM-score 0.96, RMSD 0.91 Å
- 3QQN chain A against the predicted model P35613: TM-score 0.96, RMSD 0.91 Å
Elsewhere
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