UniProt P35585
AP-1 complex subunit mu-1 (P35585)
AP-1 complex subunit mu-1 (UniProt P35585): 26 experimental structures and 1 predicted model on GenesisL1, 117 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35585
- Protein
- AP-1 complex subunit mu-1
- Experimental structures
- 26
- Predicted models
- 1
- Pockets
- 117 · 10 records with a druggable one
Structures
27 records of P35585 in the MolNFT archive: 26 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1W63 | AP1 clathrin adaptor core | x-ray diffraction | M, N, O, P, R, V | — | — |
| 1W63 | AP1 clathrin adaptor core | x-ray diffraction | M, N, O, P, R, V | — | — |
| 4EMZ | HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second… | x-ray diffraction | A, M | — | — |
| 4EMZ | HIV-1 nef in complex with MHC-I cytoplasmic domain and MU1 adaptin subunit of AP1 adaptor (second… | x-ray diffraction | A, M | — | — |
| 4EN2 | HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second… | x-ray diffraction | M, A | — | — |
| 4EN2 | HIV-1 nef in complex with MHC-I cytoplasmic domain and MU1 adaptin subunit of AP1 adaptor (second… | x-ray diffraction | M, A | — | — |
| 4HMY | Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1 | x-ray diffraction | M | — | — |
| 4HMY | Structural basis for recruitment and activation of the ap-1 clathrin adaptor complex by ARF1 | x-ray diffraction | M | — | — |
| 4P6Z | Crystal structure of the human BST2 cytoplasmic domain and the HIV-1 vpu cytoplasmic domain bound… | x-ray diffraction | M | — | — |
| 6CM9 | Structure of the cargo bound AP-1:Arf1:tetherin-Nef closed trimer monomeric subunit | electron microscopy | M | — | 10 (best 0.76) |
| 6CM9 | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef closed trimer monomeric subunit | electron microscopy | M | — | — |
| 6CRI | Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer | electron microscopy | M, W, X | — | 14 (best 0.76) |
| 6CRI | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef stable closed trimer | electron microscopy | M, W, X | — | — |
| 6D83 | Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric… | electron microscopy | M | — | 11 (best 0.76) |
| 6D83 | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef (L164A, L165A) dileucine mutant dimer monomeric… | electron microscopy | M | — | — |
| 6D84 | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef (L164A, L165A) dileucine mutant dimer | electron microscopy | M, P | — | — |
| 6DFF | Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer | electron microscopy | M | — | 10 (best 0.72) |
| 6DFF | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef monomer | electron microscopy | M | — | — |
| 7R4H | phospho-STING binding to adaptor protein complex-1 | electron microscopy | M | — | 9 (best 0.79) |
| 8D4D | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide… | electron microscopy | M, J | — | 7 (best 0.70) |
| 8D4G | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide… | electron microscopy | M, J | — | 11 (best 0.76) |
| 8D9R | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on… | electron microscopy | M, j, k, l, m, n | — | 18 (best 0.74) |
| 8D9S | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on beta-Arf1 | electron microscopy | M, j, k, l, m, n | — | 15 (best 0.76) |
| 8D9T | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on… | electron microscopy | M, i, j, k, l, m | — | — |
| 8D9U | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on… | electron microscopy | M, i, j, k, l, m | — | — |
| 8D9W | beta-Arf1 homodimeric interface within AP-1, Arf1, Nef, MHC-I lattice on narrow tubes | electron microscopy | M, X, Z, a | — | 12 (best 0.71) |
| P35585 | AlphaFold monomer V2.0 prediction for ap-1 complex subunit mu-1 (P35585) | predicted | A | — | — |
Experiment against prediction
- 4EMZ chain M against the predicted model P35585: TM-score 0.97, RMSD 1.10 Å
- 4EMZ chain M against the predicted model P35585: TM-score 0.97, RMSD 1.10 Å
- 4EN2 chain A against the predicted model P35585: TM-score 0.97, RMSD 1.21 Å
- 4EN2 chain A against the predicted model P35585: TM-score 0.97, RMSD 1.21 Å
- 8D9W chain X against the predicted model P35585: TM-score 0.96, RMSD 0.98 Å
- 8D9W chain Z against the predicted model P35585: TM-score 0.96, RMSD 0.98 Å
- 4EMZ chain A against the predicted model P35585: TM-score 0.96, RMSD 1.37 Å
- 4EMZ chain A against the predicted model P35585: TM-score 0.96, RMSD 1.37 Å
- 4EN2 chain M against the predicted model P35585: TM-score 0.96, RMSD 1.46 Å
- 4EN2 chain M against the predicted model P35585: TM-score 0.96, RMSD 1.46 Å
Elsewhere
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