UniProt P35568
P35568
P35568 (UniProt P35568): 11 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35568
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 1
Structures
12 records of P35568 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1IRS | Irs-1 ptb domain complexed with a il-4 receptor phosphopeptide, NMR, minimized average structure | solution nmr | A | — | — |
| 1IRS | Irs-1 ptb domain complexed with a il-4 receptor phosphopeptide, NMR, minimized average structure | solution nmr | A | — | — |
| 1K3A | Structure of the Insulin-like Growth Factor 1 Receptor Kinase | x-ray diffraction | B | — | — |
| 1K3A | Structure of the insulin-like growth factor 1 receptor kinase | x-ray diffraction | B | — | — |
| 1QQG | Crystal structure of the pH-ptb targeting region of irs-1 | x-ray diffraction | A, B | — | — |
| 1QQG | Crystal structure of the pH-ptb targeting region of irs-1 | x-ray diffraction | A, B | — | — |
| 2Z8C | Phosphorylated insulin receptor tyrosine kinase in complex with… | x-ray diffraction | B | — | — |
| 2Z8C | Phosphorylated insulin receptor tyrosine kinase in complex with (4… | x-ray diffraction | B | — | — |
| 5U1M | Structure of the IRS-1 PTB Domain Bound to the Juxtamembrane Region of the Insulin Receptor | x-ray diffraction | A | — | — |
| 5U1M | Structure of the irs-1 ptb domain bound to the juxtamembrane region of the insulin receptor | x-ray diffraction | A | ACE | — |
| 6BNT | Crystal structure of AP2 MU1 adaptin C-terminal domain with irs-1 peptide | x-ray diffraction | B | — | — |
| P35568 | AlphaFold monomer V2.0 prediction for insulin receptor substrate 1 (P35568) | predicted | A | — | — |
Ligands
- ACE · Acetyl group · in 1 record
Experiment against prediction
- 1QQG chain A against the predicted model P35568: TM-score 1.00, RMSD 0.32 Å
- 1QQG chain A against the predicted model P35568: TM-score 1.00, RMSD 0.32 Å
- 1QQG chain B against the predicted model P35568: TM-score 0.99, RMSD 0.46 Å
- 1QQG chain B against the predicted model P35568: TM-score 0.99, RMSD 0.46 Å
- 5U1M chain A against the predicted model P35568: TM-score 0.98, RMSD 0.61 Å
- 5U1M chain A against the predicted model P35568: TM-score 0.98, RMSD 0.61 Å
- 1IRS chain A against the predicted model P35568: TM-score 0.89, RMSD 1.84 Å
- 1IRS chain A against the predicted model P35568: TM-score 0.89, RMSD 1.84 Å
- 6BNT chain B against the predicted model P35568: TM-score 0.54, RMSD 1.22 Å
- 2Z8C chain B against the predicted model P35568: TM-score 0.54, RMSD 0.49 Å
Elsewhere
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