UniProt P35475
P35475
P35475 (UniProt P35475): 22 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35475
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 6
Structures
23 records of P35475 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3W81 | Human alpha-l-iduronidase | x-ray diffraction | A, B | — | — |
| 3W81 | Human alpha-L-iduronidase | x-ray diffraction | A, B | — | — |
| 3W82 | Human alpha-L-iduronidase in complex with iduronic acid | x-ray diffraction | A, B | — | — |
| 3W82 | Human alpha-L-iduronidase in complex with iduronic acid | x-ray diffraction | A, B | — | — |
| 4KGJ | Crystal structure of human alpha-L-iduronidase complex with 5-fluoro-alpha-L-idopyranosyluronic… | x-ray diffraction | A, B | — | — |
| 4KGJ | Crystal structure of human alpha-L-iduronidase complex with 5-fluoro- alpha-L-idopyranosyluronic… | x-ray diffraction | A, B | — | — |
| 4KGL | Crystal structure of human alpha-L-iduronidase complex with… | x-ray diffraction | A, B | — | — |
| 4KGL | Crystal structure of human alpha-L-iduronidase complex with [2R,3R,4R… | x-ray diffraction | A, B | — | — |
| 4KH2 | Crystal structure of human alpha-L-iduronidase complex with… | x-ray diffraction | A, B | — | — |
| 4KH2 | Crystal structure of human alpha-L-iduronidase complex with 2-deoxy-2… | x-ray diffraction | A, B | — | — |
| 4MJ2 | Crystal structure of apo-iduronidase in the R3 form | x-ray diffraction | A, B | — | — |
| 4MJ2 | Crystal structure of apo-iduronidase in the R3 form | x-ray diffraction | A, B | — | — |
| 4MJ4 | Human iduronidase apo structure P21 form | x-ray diffraction | A | — | — |
| 4MJ4 | Human iduronidase apo structure P21 form | x-ray diffraction | A | — | — |
| 4OBR | Crystal structure of human alpha-L-iduronidase complex with alpha-L-iduronic acid | x-ray diffraction | A, B | — | — |
| 4OBR | Crystal structure of human alpha-L-iduronidase complex with alpha-L- iduronic acid | x-ray diffraction | A, B | — | — |
| 4OBS | Crystal structure of human alpha-L-iduronidase in the P212121 form | x-ray diffraction | A | — | — |
| 4OBS | Crystal structure of human alpha-L-iduronidase in the P212121 form | x-ray diffraction | A | — | — |
| 6I6R | New Irreversible a-l-Iduronidase Inhibitors and Activity-Based Probes | x-ray diffraction | A, B | NAG, BMA, H62, CL | — |
| 6I6R | New irreversible a-L-iduronidase inhibitors and activity-based probes | x-ray diffraction | A, B | NAG, BMA, H62, CL | — |
| 6I6X | New Irreversible a-l-Iduronidase Inhibitors and Activity-Based Probes | x-ray diffraction | A, B | NAG, BMA, MAN, H6B, CL | — |
| 6I6X | New irreversible a-L-iduronidase inhibitors and activity-based probes | x-ray diffraction | A, B | NAG, BMA, MAN, H6B, CL | — |
| P35475 | AlphaFold monomer V2.0 prediction for alpha-L-iduronidase (P35475) | predicted | A | — | — |
Ligands
- BMA · beta-D-mannopyranose · in 4 records
- CL · Chloride ion · in 4 records
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
- H62 · (1~{R},2~{R},3~{R},4~{S},6~{S})-6-azanyl-2,3,4-tris(oxidanyl)cyclohexane-1-carboxylic acid · in 2 records
- H6B · (1~{R},2~{R},3~{R},4~{S},5~{S},6~{R})-7-methyl-3,4,5-tris(oxidanyl)-7-azabicyclo[4.1.0]heptane-2-carboxylic acid · in 2 records
- MAN · alpha-D-mannopyranose · in 2 records
Experiment against prediction
- 6I6X chain A against the predicted model P35475: TM-score 1.00, RMSD 0.30 Å
- 6I6X chain A against the predicted model P35475: TM-score 1.00, RMSD 0.30 Å
- 3W81 chain A against the predicted model P35475: TM-score 1.00, RMSD 0.32 Å
- 3W81 chain A against the predicted model P35475: TM-score 1.00, RMSD 0.32 Å
- 4MJ2 chain B against the predicted model P35475: TM-score 1.00, RMSD 0.34 Å
- 4MJ2 chain B against the predicted model P35475: TM-score 1.00, RMSD 0.34 Å
- 4OBR chain B against the predicted model P35475: TM-score 1.00, RMSD 0.34 Å
- 4OBR chain B against the predicted model P35475: TM-score 1.00, RMSD 0.34 Å
- 3W82 chain A against the predicted model P35475: TM-score 1.00, RMSD 0.34 Å
- 3W82 chain A against the predicted model P35475: TM-score 1.00, RMSD 0.34 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.