UniProt P35465
Serine/threonine-protein kinase PAK 1 (P35465)
Serine/threonine-protein kinase PAK 1 (UniProt P35465), EC 2.7.11.1: 2 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35465
- Protein
- Serine/threonine-protein kinase PAK 1
- EC
- 2.7.11.1
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 6 · 3 records with a druggable one
Structures
3 records of P35465 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1E0A | Cdc42 complexed with the GTPase binding domain of p21 activated kinase | solution nmr | B | — | 1 (best 0.55) |
| 1E0A | CDC42 complexed with the GTPase binding domain of P21 activated kinase | solution nmr | B | — | 1 (best 0.55) |
| P35465 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase pak 1 (P35465) | predicted | A | — | 4 (best 0.79) |
Experiment against prediction
- 1E0A chain B against the predicted model P35465: TM-score 0.40, RMSD 2.12 Å
- 1E0A chain B against the predicted model P35465: TM-score 0.40, RMSD 2.12 Å
Elsewhere
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