UniProt P35462
Green fluorescent protein,D(3) dopamine receptor (P35462)
Green fluorescent protein,D(3) dopamine receptor (UniProt P35462): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P35462
- Protein
- Green fluorescent protein,D(3) dopamine receptor
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 15 · 4 records with a druggable one
Structures
9 records of P35462 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3PBL | Structure of the human dopamine D3 receptor in complex with eticlopride | x-ray diffraction | A, B | — | — |
| 3PBL | Structure of the human dopamine D3 receptor in complex with eticlopride | x-ray diffraction | A, B | — | — |
| 7CMU | Dopamine Receptor D3R-Gi-Pramipexole complex | electron microscopy | R | G6L | 4 (best 0.73) |
| 7CMU | Dopamine receptor D3R-gi-pramipexole complex | electron microscopy | R | G6L | — |
| 7CMV | Dopamine Receptor D3R-Gi-PD128907 complex | electron microscopy | R | G6O | 3 (best 0.74) |
| 7CMV | Dopamine receptor D3R-gi-PD128907 complex | electron microscopy | R | G6O | — |
| 9F33 | Cryo-EM structure of Dopamine 3 Receptor:Go complex bound to bitopic FOB02-04A - Conformation A | electron microscopy | R | A1H9N | 4 (best 0.74) |
| 9F34 | Cryo-EM structure of Dopamine 3 receptor:Go complex bound to bitopic FOB02-04A - Conformation B | electron microscopy | R | A1H9N | 4 (best 0.74) |
| P35462 | AlphaFold monomer V2.0 prediction for D(3) dopamine receptor (P35462) | predicted | A | — | — |
Ligands
- A1H9N · N-[2-[(1R,2S)-2-[[(2S,5S)-2-(6-azanylpyridin-3-yl)-5-methyl-morpholin-4-yl]methyl]cyclopropyl]ethyl]-1H-indole-2-carboxamide · in 2 records
- G6L · (6S)-N6-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2, 6-diamine · in 2 records
- G6O · (4aR,10bR)-4-propyl-3,4a,5,10b-tetrahydro-2H-chromeno[4,3-b][1,4]oxazin-9-ol · in 2 records
Experiment against prediction
- 9F33 chain R against the predicted model P35462: TM-score 0.94, RMSD 1.86 Å
- 9F34 chain R against the predicted model P35462: TM-score 0.94, RMSD 1.87 Å
- 7CMV chain R against the predicted model P35462: TM-score 0.93, RMSD 2.01 Å
- 7CMV chain R against the predicted model P35462: TM-score 0.93, RMSD 2.01 Å
- 7CMU chain R against the predicted model P35462: TM-score 0.93, RMSD 2.00 Å
- 7CMU chain R against the predicted model P35462: TM-score 0.93, RMSD 2.00 Å
- 3PBL chain A against the predicted model P35462: TM-score 0.68, RMSD 2.34 Å
- 3PBL chain A against the predicted model P35462: TM-score 0.68, RMSD 2.34 Å
- 3PBL chain B against the predicted model P35462: TM-score 0.67, RMSD 3.01 Å
- 3PBL chain B against the predicted model P35462: TM-score 0.67, RMSD 3.01 Å
Elsewhere
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