UniProt P35348
Endolysin,Alpha-1A adrenergic receptor (P35348)
Endolysin,Alpha-1A adrenergic receptor (UniProt P35348), EC 3.2.1.17: 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P35348
- Protein
- Endolysin,Alpha-1A adrenergic receptor
- EC
- 3.2.1.17
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 16 · 3 records with a druggable one
Structures
4 records of P35348 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8HN1 | Cryo-EM structure of AdTx1-alpha1AAR-Nb6 | electron microscopy | A | — | 3 (best 0.85) |
| 8THK | Cryo-EM structure of A61603-bound alpha-1A-adrenergic receptor in complex with heterotrimeric… | electron microscopy | R | CGZ | 7 (best 0.82) |
| 8THL | Cryo-EM structure of epinephrine-bound alpha-1A-adrenergic receptor in complex with heterotrimeric… | electron microscopy | R | ALE | 6 (best 0.78) |
| P35348 | AlphaFold monomer V2.0 prediction for alpha-1A adrenergic receptor (P35348) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8THK chain R against the predicted model P35348: TM-score 0.97, RMSD 1.30 Å
- 8THL chain R against the predicted model P35348: TM-score 0.96, RMSD 1.30 Å
- 8HN1 chain A against the predicted model P35348: TM-score 0.94, RMSD 1.81 Å
Elsewhere
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