UniProt P35244
Replication protein A 14 kDa subunit (P35244)
Replication protein A 14 kDa subunit (UniProt P35244): 13 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P35244
- Protein
- Replication protein A 14 kDa subunit
- Experimental structures
- 13
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
14 records of P35244 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1L1O | Structure of the human Replication Protein A (RPA) trimerization core | x-ray diffraction | A, D | — | — |
| 1L1O | Structure of the human replication protein a (rpa) trimerization core | x-ray diffraction | A, D | — | — |
| 1QUQ | Complex of replication protein a subunits RPA14 and RPA32 | x-ray diffraction | B, D | — | — |
| 1QUQ | Complex of replication protein a subunits RPA14 and RPA32 | x-ray diffraction | B, D | — | — |
| 2PI2 | Full-length Replication protein A subunits RPA14 and RPA32 | x-ray diffraction | E, F, G, H | — | — |
| 2PI2 | Full-length replication protein a subunits RPA14 and RPA32 | x-ray diffraction | E, F, G, H | — | — |
| 2PQA | Crystal Structure of Full-length Human RPA 14/32 Heterodimer | x-ray diffraction | B, D | — | — |
| 2PQA | Crystal structure of full-length human rpa 14/32 heterodimer | x-ray diffraction | B, D | — | — |
| 2Z6K | Crystal structure of full-length human RPA14/32 heterodimer | x-ray diffraction | C, D | — | — |
| 2Z6K | Crystal structure of full-length human RPA14/32 heterodimer | x-ray diffraction | C, D | — | — |
| 3KDF | X-ray Crystal Structure of the Human Replication Protein A Complex from Wheat Germ Cell Free… | x-ray diffraction | A, C | — | — |
| 3KDF | X-ray crystal structure of the human replication protein a complex from wheat germ cell free… | x-ray diffraction | A, C | — | — |
| 8RK2 | Human Replication protein A (RPA; trimeric core) - ssDNA complex | electron microscopy | C | — | 3 (best 0.81) |
| P35244 | AlphaFold monomer V2.0 prediction for replication protein a 14 kda subunit (P35244) | predicted | A | — | — |
Experiment against prediction
- 2PQA chain D against the predicted model P35244: TM-score 0.99, RMSD 0.48 Å
- 2PQA chain D against the predicted model P35244: TM-score 0.99, RMSD 0.48 Å
- 2PQA chain B against the predicted model P35244: TM-score 0.98, RMSD 0.51 Å
- 2PQA chain B against the predicted model P35244: TM-score 0.98, RMSD 0.51 Å
- 2PI2 chain E against the predicted model P35244: TM-score 0.98, RMSD 0.72 Å
- 2PI2 chain E against the predicted model P35244: TM-score 0.98, RMSD 0.72 Å
- 1QUQ chain D against the predicted model P35244: TM-score 0.98, RMSD 0.62 Å
- 1QUQ chain D against the predicted model P35244: TM-score 0.98, RMSD 0.62 Å
- 3KDF chain C against the predicted model P35244: TM-score 0.98, RMSD 0.79 Å
- 3KDF chain C against the predicted model P35244: TM-score 0.98, RMSD 0.79 Å
Elsewhere
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