UniProt P34914
Epoxide hydrolase (P34914)
Epoxide hydrolase (UniProt P34914), EC 3.3.2.3: 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 78 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P34914
- Protein
- Epoxide hydrolase
- EC
- 3.3.2.3
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 78 · 9 records with a druggable one
Structures
9 records of P34914 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1CQZ | Crystal structure of murine soluble epoxide hydrolase. | x-ray diffraction | A, B | — | 10 (best 0.84) |
| 1CQZ | Crystal structure of murine soluble epoxide hydrolase. | x-ray diffraction | A, B | — | 10 (best 0.84) |
| 1CR6 | Crystal structure of murine soluble epoxide hydrolase complexed with cpu inhibitor | x-ray diffraction | A, B | CPU | 7 (best 0.84) |
| 1CR6 | Crystal structure of murine soluble epoxide hydrolase complexed with cpu inhibitor | x-ray diffraction | A, B | CPU | 7 (best 0.84) |
| 1EK1 | Crystal structure of murine soluble epoxide hydrolase complexed with ciu inhibitor | x-ray diffraction | A, B | CIU | 9 (best 0.82) |
| 1EK1 | Crystal structure of murine soluble epoxide hydrolase complexed with ciu inhibitor | x-ray diffraction | A, B | CIU | 9 (best 0.82) |
| 1EK2 | Crystal structure of murine soluble epoxide hydrolase complexed with cdu inhibitor | x-ray diffraction | A, B | CDU | 11 (best 0.85) |
| 1EK2 | Crystal structure of murine soluble epoxide hydrolase complexed with cdu inhibitor | x-ray diffraction | A, B | CDU | 11 (best 0.85) |
| P34914 | AlphaFold monomer V2.0 prediction for bifunctional epoxide hydrolase 2 (P34914) | predicted | A | — | 4 (best 0.82) |
Ligands
Experiment against prediction
- 1CR6 chain A against the predicted model P34914: TM-score 0.98, RMSD 1.19 Å
- 1CR6 chain A against the predicted model P34914: TM-score 0.98, RMSD 1.19 Å
- 1CQZ chain A against the predicted model P34914: TM-score 0.98, RMSD 1.20 Å
- 1CQZ chain A against the predicted model P34914: TM-score 0.98, RMSD 1.20 Å
- 1EK2 chain A against the predicted model P34914: TM-score 0.97, RMSD 1.25 Å
- 1EK2 chain A against the predicted model P34914: TM-score 0.97, RMSD 1.25 Å
- 1EK1 chain A against the predicted model P34914: TM-score 0.97, RMSD 1.33 Å
- 1EK1 chain A against the predicted model P34914: TM-score 0.97, RMSD 1.33 Å
- 1CR6 chain B against the predicted model P34914: TM-score 0.96, RMSD 1.79 Å
- 1CR6 chain B against the predicted model P34914: TM-score 0.96, RMSD 1.79 Å
Elsewhere
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