UniProt P34413
C-mannosyltransferase dpy-19 (P34413)
C-mannosyltransferase dpy-19 (UniProt P34413), EC 2.4.1.-: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P34413
- Protein
- C-mannosyltransferase dpy-19
- EC
- 2.4.1.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 9 · 1 record with a druggable one
Structures
3 records of P34413 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7ZLI | Cryo-EM structure of C-mannosyltransferase CeDPY19, in complex with Dol25-P-Man and bound to… | electron microscopy | A | IZY | 9 (best 0.80) |
| 7ZLJ | Cryo-EM structure of C-mannosyltransferase CeDPY19, in ternary complex with Dol25-P-C-Man and… | electron microscopy | A | IZU | — |
| P34413 | AlphaFold monomer V2.0 prediction for C-mannosyltransferase dpy-19 (P34413) | predicted | A | — | — |
Ligands
- IZU · [(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]methyl-[(3~{S},6~{E},10~{Z},14~{E})-3,7,11,15,19-pentamethylicosa-6,10,14,18-tetraenoxy]phosphinic acid · in 1 record
- IZY · [(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl] [(3~{S},6~{Z},10~{E},14~{E})-3,7,11,15,19-pentamethylicosa-6,10,14,18-tetraenyl] hydrogen phosphate · in 1 record
Experiment against prediction
- 7ZLJ chain A against the predicted model P34413: TM-score 0.99, RMSD 0.99 Å
- 7ZLI chain A against the predicted model P34413: TM-score 0.99, RMSD 1.04 Å
Elsewhere
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