UniProt P33993
DNA replication licensing factor MCM7 (P33993)
DNA replication licensing factor MCM7 (UniProt P33993), EC 3.6.4.12: 14 experimental structures on GenesisL1, 5 ligands bound, 92 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P33993
- Protein
- DNA replication licensing factor MCM7
- EC
- 3.6.4.12
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 92 · 11 records with a druggable one
Structures
14 records of P33993 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6XTX | CryoEM structure of human CMG bound to ATPgammaS and DNA | electron microscopy | 7 | AGS, ZN, MG | 8 (best 0.82) |
| 6XTX | Cryoem structure of human cmg bound to atpgammas and DNA | electron microscopy | 7 | AGS, ZN, MG | — |
| 6XTY | Cryoem structure of human cmg bound to and-1 (cmga) | electron microscopy | 7 | ZN | — |
| 7PLO | H. sapiens replisome-CUL2/LRR1 complex | electron microscopy | 7 | ZN | 8 (best 0.86) |
| 8S09 | H. sapiens MCM2-7 double hexamer bound to double stranded DNA | electron microscopy | 7, F | ADP, MG, ZN | 10 (best 0.89) |
| 8S0A | H. sapiens MCM2-7 hexamer bound to double stranded DNA | electron microscopy | 7 | ADP, MG, ZN | 10 (best 0.85) |
| 8S0B | H. sapiens MCM bound to double stranded DNA and ORC6 as part of the MCM-ORC complex | electron microscopy | 7 | ADP, MG, AGS, ZN | 11 (best 0.86) |
| 8S0D | H. sapiens MCM bound to double stranded DNA and ORC1-6 | electron microscopy | 7 | ADP, MG, AGS, ZN | 8 (best 0.87) |
| 8S0E | H. sapiens OCCM bound to double stranded DNA | electron microscopy | 7 | — | 3 (best 0.82) |
| 8S0F | H. sapiens OC1M bound to double stranded DNA | electron microscopy | 7 | — | 2 (best 0.85) |
| 8W0E | Cryo-EM structure of a human MCM2-7 single hexamer on dsDNA | electron microscopy | 7 | ZN, MG, ADP | 8 (best 0.88) |
| 8W0F | Cryo-EM structure of a human MCM2-7 double hexamer on dsDNA | electron microscopy | 7, F | ZN, MG, ADP | 15 (best 0.88) |
| 8W0I | Cryo-EM structure of the human MCM2-7 heterohexamer | electron microscopy | 7 | ATP, ZN, MG | 9 (best 0.84) |
| P33993 | AlphaFold monomer V2.0 prediction for DNA replication licensing factor MCM7 (P33993) | — | — | — |
Ligands
Elsewhere
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