UniProt P33895
Kinetochore protein NUF2 (P33895)
Kinetochore protein NUF2 (UniProt P33895), EC 2.7.12.2: 9 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 58 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P33895
- Protein
- Kinetochore protein NUF2
- EC
- 2.7.12.2
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 58 · 9 records with a druggable one
Structures
10 records of P33895 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5TCS | Crystal structure of a dwarf NDC80 tetramer | x-ray diffraction | B | MG | 5 (best 0.59) |
| 5TD8 | Crystal structure of an Extended Dwarf Ndc80 Complex | x-ray diffraction | B | HG | 5 (best 0.72) |
| 5TD8 | Crystal structure of an extended dwarf NDC80 complex | x-ray diffraction | B | HG | 5 (best 0.72) |
| 8G0Q | Crystal structure of the yeast Ndc80:Nuf2 head region with a bound Dam1 segment | x-ray diffraction | B, D | — | 14 (best 0.80) |
| 8Q84 | Outer kinetochore Dam1 protomer dimer Ndc80-Nuf2 coiled-coil complex | electron microscopy | B, G | — | 2 (best 0.68) |
| 8Q85 | Outer kinetochore Dam1 protomer monomer Ndc80-Nuf2 coiled-coil complex | electron microscopy | G | — | 2 (best 0.67) |
| 8QAU | Outer kinetochore Ndc80-Dam1 alpha/beta-tubulin complex | electron microscopy | B | — | 5 (best 0.75) |
| 8V10 | Structure of a Saccharomyces cerevisiae Mps1 peptide bound to dwarf Ndc80 Complex | x-ray diffraction | B | — | 6 (best 0.62) |
| 8V11 | Structure of a Saccharomyces cerevisiae Ipl1 peptide Bound to dwarf Ndc80 complex | x-ray diffraction | B, F | — | 14 (best 0.76) |
| P33895 | AlphaFold monomer V2.0 prediction for kinetochore protein NUF2 (P33895) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8QAU chain B against the predicted model P33895: TM-score 0.80, RMSD 2.33 Å
- 8G0Q chain D against the predicted model P33895: TM-score 0.76, RMSD 2.87 Å
- 5TD8 chain B against the predicted model P33895: TM-score 0.74, RMSD 2.85 Å
- 5TD8 chain B against the predicted model P33895: TM-score 0.74, RMSD 2.85 Å
- 8V11 chain F against the predicted model P33895: TM-score 0.73, RMSD 2.58 Å
- 5TCS chain B against the predicted model P33895: TM-score 0.73, RMSD 2.41 Å
- 8V11 chain B against the predicted model P33895: TM-score 0.71, RMSD 2.59 Å
- 8V10 chain B against the predicted model P33895: TM-score 0.71, RMSD 2.58 Å
- 8Q85 chain G against the predicted model P33895: TM-score 0.69, RMSD 2.93 Å
- 8G0Q chain B against the predicted model P33895: TM-score 0.66, RMSD 2.94 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.