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UniProt P33775

Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (P33775)

Dolichyl-phosphate-mannose--protein mannosyltransferase 1 (UniProt P33775), EC 2.4.1.109: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 26 pockets. Binding sites, druggability and experiment…

UniProt
P33775
Protein
Dolichyl-phosphate-mannose--protein mannosyltransferase 1
EC
2.4.1.109
Experimental structures
4
Predicted models
1
Ligands
3
Pockets
26 · 3 records with a druggable one

Structures

5 records of P33775 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6P25Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor…electron microscopyANAG, CPL, NNM8 (best 0.75)
6P25Structure of S. cerevisiae protein O-mannosyltransferase PMT1-PMT2 complex bound to the sugar donor…electron microscopyANAG, CPL, NNM—
6P2RStructure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donorelectron microscopyANAG, CPL, NNM8 (best 0.75)
6P2RStructure of S. cerevisiae protein O-mannosyltransferase PMT1-PMT2 complex bound to the sugar donorelectron microscopyANAG, CPL, NNM—
P33775AlphaFold monomer V2.0 prediction for dolichyl-phosphate-mannose-- protein mannosyltransferase 1…predictedA—10 (best 0.77)

Ligands

  • CPL · 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine · in 4 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
  • NNM · (3R)-3,31-dimethyl-7,11,15,19,23,27-hexamethylidenedotriacont-31-en-1-yl dihydrogen phosphate · in 4 records

Experiment against prediction

Elsewhere

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