UniProt P33755
Nuclear protein localization protein 4 (P33755)
Nuclear protein localization protein 4 (UniProt P33755): 13 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 50 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P33755
- Protein
- Nuclear protein localization protein 4
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 50 · 7 records with a druggable one
Structures
14 records of P33755 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6JWH | Yeast Npl4 zinc finger, MPN and CTD domains | x-ray diffraction | A | ZN | 6 (best 0.56) |
| 6JWH | Yeast NPL4 zinc finger, mpn and ctd domains | x-ray diffraction | A | ZN | — |
| 6JWI | Yeast Npl4 in complex with Lys48-linked diubiquitin | x-ray diffraction | A, E | GLC, ZN, BCN | 18 (best 0.77) |
| 6JWI | Yeast NPL4 in complex with LYS48-linked diubiquitin | x-ray diffraction | A, E | GLC, ZN, BCN | — |
| 6JWJ | Npl4 in complex with Ufd1 | x-ray diffraction | A | ZN | 5 (best 0.67) |
| 6JWJ | NPL4 in complex with UFD1 | x-ray diffraction | A | ZN | — |
| 6OA9 | Cdc48-Npl4 complex processing poly-ubiquitinated substrate in the presence of ATP | electron microscopy | G | ZN | — |
| 6OA9 | CDC48-NPL4 complex processing poly-ubiquitinated substrate in the presence of ATP | electron microscopy | G | ZN | — |
| 6OAA | CDC48-NPL4 complex processing poly-ubiquitinated substrate in the presence of ADP-befx, state 1 | electron microscopy | G | — | — |
| 8DAR | Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex unbound but in the presence of… | electron microscopy | G | ZN | 4 (best 0.86) |
| 8DAS | Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two ubiquitin moieties in presence of… | electron microscopy | G | ZN | 5 (best 0.86) |
| 8DAU | Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to two folded ubiquitin moieties and one… | electron microscopy | G | ZN | 6 (best 0.83) |
| 8DAW | Saccharomyces cerevisiae Ufd1/Npl4/Cdc48 complex bound to three ubiquitin moieties and one unfolded… | electron microscopy | G | ZN | — |
| P33755 | AlphaFold monomer V2.0 prediction for nuclear protein localization protein 4 (P33755) | predicted | A | — | 6 (best 0.54) |
Ligands
Experiment against prediction
- 6JWH chain A against the predicted model P33755: TM-score 1.00, RMSD 0.48 Å
- 6JWH chain A against the predicted model P33755: TM-score 1.00, RMSD 0.48 Å
- 6JWJ chain A against the predicted model P33755: TM-score 0.99, RMSD 1.00 Å
- 6JWJ chain A against the predicted model P33755: TM-score 0.99, RMSD 1.00 Å
- 6JWI chain A against the predicted model P33755: TM-score 0.98, RMSD 1.12 Å
- 6JWI chain A against the predicted model P33755: TM-score 0.98, RMSD 1.12 Å
- 6JWI chain E against the predicted model P33755: TM-score 0.98, RMSD 1.14 Å
- 6JWI chain E against the predicted model P33755: TM-score 0.98, RMSD 1.14 Å
- 8DAS chain G against the predicted model P33755: TM-score 0.98, RMSD 1.22 Å
- 8DAR chain G against the predicted model P33755: TM-score 0.98, RMSD 1.25 Å
Elsewhere
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