UniProt P33201
Ribosome assembly factor MRT4 (P33201)
Ribosome assembly factor MRT4 (UniProt P33201): 19 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P33201
- Protein
- Ribosome assembly factor MRT4
- Experimental structures
- 19
- Predicted models
- 1
- Pockets
- 6 · 4 records with a druggable one
Structures
20 records of P33201 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCT | Cryo-em structure of eukaryotic pre-60S ribosomal subunits | electron microscopy | W | — | — |
| 4V7F | Arx1 pre-60S particle. | electron microscopy | n | — | — |
| 4V7F | ARX1 pre-60S particle. | electron microscopy | n | — | — |
| 5JCS | Cryo-EM structure of the RIX1-REA1 pre-60S particle | electron microscopy | n | — | — |
| 6ELZ | State E (TAP-Flag-Ytm1 E80A) - Visualizing the assembly pathway of nucleolar pre-60S ribosomes | electron microscopy | W | — | — |
| 6EM5 | State D architectural model (Nsa1-TAP Flag-Ytm1) - Visualizing the assembly pathway of nucleolar… | electron microscopy | W | — | — |
| 6EM5 | State D architectural model (NSA1-tap flag-YTM1) - visualizing the assembly pathway of nucleolar… | electron microscopy | W | — | — |
| 6M62 | Cryo-Em structure of eukaryotic pre-60S ribosome subunit from Saccharomyces cerevisiae rpf2 delta… | electron microscopy | W | — | — |
| 6N8J | Cryo-EM structure of late nuclear (LN) pre-60S ribosomal subunit | electron microscopy | W | — | — |
| 6N8K | Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunit | electron microscopy | W | — | — |
| 6N8L | Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunit | electron microscopy | W | — | — |
| 7NAC | State E2 nucleolar 60S ribosomal biogenesis intermediate - Composite model | electron microscopy | W | — | — |
| 7OH3 | Nog1-TAP associated immature ribosomal particle population B from S. cerevisiae | electron microscopy | W | — | — |
| 7OHP | Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL25 expression shut… | electron microscopy | W | — | 1 (best 0.80) |
| 7OHR | Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae | electron microscopy | W | — | 1 (best 0.84) |
| 7OHS | Nog1-TAP associated immature ribosomal particle population F from S. cerevisiae | electron microscopy | W | — | — |
| 7UG6 | Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922 | electron microscopy | W | — | 1 (best 0.87) |
| 8V83 | 60S ribosome biogenesis intermediate (Dbp10 pre-catalytic structure - Overall map) | electron microscopy | W | — | 2 (best 0.83) |
| 8V84 | 60S ribosome biogenesis intermediate (Dbp10 catalytic structure - Overall map) | electron microscopy | W | — | — |
| P33201 | AlphaFold monomer V2.0 prediction for ribosome assembly factor MRT4 (P33201) | predicted | A | — | 1 (best 0.36) |
Experiment against prediction
- 6N8L chain W against the predicted model P33201: TM-score 0.94, RMSD 1.09 Å
- 6N8K chain W against the predicted model P33201: TM-score 0.92, RMSD 1.88 Å
- 8V84 chain W against the predicted model P33201: TM-score 0.91, RMSD 1.74 Å
- 7NAC chain W against the predicted model P33201: TM-score 0.90, RMSD 1.79 Å
- 6EM5 chain W against the predicted model P33201: TM-score 0.90, RMSD 1.79 Å
- 6EM5 chain W against the predicted model P33201: TM-score 0.90, RMSD 1.79 Å
- 6ELZ chain W against the predicted model P33201: TM-score 0.90, RMSD 1.79 Å
- 7OHR chain W against the predicted model P33201: TM-score 0.90, RMSD 1.86 Å
- 8V83 chain W against the predicted model P33201: TM-score 0.90, RMSD 1.83 Å
- 7OH3 chain W against the predicted model P33201: TM-score 0.90, RMSD 1.70 Å
Elsewhere
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