UniProt P32927
Cytokine receptor common subunit beta (P32927)
Cytokine receptor common subunit beta (UniProt P32927): 17 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32927
- Protein
- Cytokine receptor common subunit beta
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 23 · 3 records with a druggable one
Structures
18 records of P32927 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1C8P | NMR structure of the ligand binding domain of the common beta-chain in the gm-csf, il-3 and il-5… | solution nmr | A | — | — |
| 1C8P | NMR structure of the ligand binding domain of the common beta-chain in the gm-csf, il-3 and il-5… | solution nmr | A | — | — |
| 1EGJ | Domain 4 of the beta common chain in complex with an antibody | x-ray diffraction | A | — | — |
| 1EGJ | Domain 4 of the beta common chain in complex with an antibody | x-ray diffraction | A | — | — |
| 1GH7 | Crystal structure of the complete extracellular domain of the beta-common receptor of il-3, il-5… | x-ray diffraction | A, B | — | — |
| 1GH7 | Crystal structure of the complete extracellular domain of the beta- common receptor of il-3, il-5… | x-ray diffraction | A, B | — | — |
| 2NA8 | Transmembrane Structure of the Cytokine Receptor Common Subunit beta | solution nmr | A | — | — |
| 2NA8 | Transmembrane structure of the cytokine receptor common subunit beta | solution nmr | A | — | — |
| 2NA9 | Transmembrane Structure of the P441A Mutant of the Cytokine Receptor Common Subunit beta | solution nmr | A | — | — |
| 2NA9 | Transmembrane structure of the P441A mutant of the cytokine receptor common subunit beta | solution nmr | A | — | — |
| 4NKQ | Structure of a Cytokine Receptor Complex | x-ray diffraction | A | — | — |
| 4NKQ | Structure of a cytokine receptor complex | x-ray diffraction | A | — | — |
| 5DWU | Beta common receptor in complex with a Fab | x-ray diffraction | A, B | NAG | 6 (best 0.66) |
| 5DWU | Beta common receptor in complex with a Fab | x-ray diffraction | A, B | — | — |
| 6NMY | A Cytokine-receptor complex | x-ray diffraction | A, C, B, D | NAG | 13 (best 0.79) |
| 6NMY | A cytokine-receptor complex | x-ray diffraction | A, C, B, D | NAG | — |
| 8TLD | Structure of the IL-5 Signaling Complex | electron microscopy | B, E | — | 4 (best 0.63) |
| P32927 | AlphaFold monomer V2.0 prediction for cytokine receptor common subunit beta (P32927) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 3 records
Experiment against prediction
- 6NMY chain D against the predicted model P32927: TM-score 0.97, RMSD 0.91 Å
- 6NMY chain D against the predicted model P32927: TM-score 0.97, RMSD 0.91 Å
- 8TLD chain E against the predicted model P32927: TM-score 0.97, RMSD 0.82 Å
- 6NMY chain B against the predicted model P32927: TM-score 0.97, RMSD 0.99 Å
- 6NMY chain B against the predicted model P32927: TM-score 0.97, RMSD 0.99 Å
- 8TLD chain B against the predicted model P32927: TM-score 0.95, RMSD 0.88 Å
- 6NMY chain A against the predicted model P32927: TM-score 0.94, RMSD 1.38 Å
- 6NMY chain A against the predicted model P32927: TM-score 0.94, RMSD 1.38 Å
- 5DWU chain B against the predicted model P32927: TM-score 0.94, RMSD 1.31 Å
- 5DWU chain B against the predicted model P32927: TM-score 0.94, RMSD 1.31 Å
Elsewhere
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