UniProt P32915
Protein transport protein SEC61 (P32915)
Protein transport protein SEC61 (UniProt P32915): 24 experimental structures and 1 predicted model on GenesisL1, 97 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32915
- Protein
- Protein transport protein SEC61
- Experimental structures
- 24
- Predicted models
- 1
- Pockets
- 97 · 10 records with a druggable one
Structures
25 records of P32915 in the MolNFT archive: 24 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6N3Q | Cryo-EM structure of the yeast Sec complex | electron microscopy | A | — | 8 (best 0.65) |
| 6N3Q | Cryo-EM structure of the yeast sec complex | electron microscopy | A | — | — |
| 6ND1 | CryoEM structure of the Sec Complex from yeast | electron microscopy | B | — | — |
| 6ND1 | Cryoem structure of the sec complex from yeast | electron microscopy | B | — | — |
| 7AFT | Cryo-EM structure of the signal sequence-engaged post-translational sec translocon | electron microscopy | A | — | — |
| 7KAH | Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class without Sec62 | electron microscopy | A | — | 10 (best 0.70) |
| 7KAH | Cryo-EM structure of the sec complex from S. cerevisiae, wild-type, class without SEC62 | electron microscopy | A | — | — |
| 7KAI | Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation… | electron microscopy | A | — | 12 (best 0.61) |
| 7KAI | Cryo-EM structure of the sec complex from S. cerevisiae, wild-type, class with SEC62, conformation… | electron microscopy | A | — | — |
| 7KAJ | Cryo-EM structure of the Sec complex from S. cerevisiae, wild-type, class with Sec62, conformation… | electron microscopy | A | — | 10 (best 0.59) |
| 7KAJ | Cryo-EM structure of the sec complex from S. cerevisiae, wild-type, class with SEC62, conformation… | electron microscopy | A | — | — |
| 7KAO | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class without Sec62 | electron microscopy | A | — | 10 (best 0.71) |
| 7KAO | Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore mutant, class without SEC62 | electron microscopy | A | — | — |
| 7KAP | Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore mutant, class with SEC62… | electron microscopy | A | — | — |
| 7KAQ | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore mutant, class with Sec62… | electron microscopy | A | — | 12 (best 0.68) |
| 7KAQ | Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore mutant, class with SEC62… | electron microscopy | A | — | — |
| 7KAR | Cryo-EM structure of the sec complex from S. cerevisiae, SEC63 FN3 mutant, class without SEC62 | electron microscopy | A | — | — |
| 7KAS | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec63 FN3 mutant, class with Sec62 | electron microscopy | A | — | 10 (best 0.59) |
| 7KAS | Cryo-EM structure of the sec complex from S. cerevisiae, SEC63 FN3 mutant, class with SEC62 | electron microscopy | A | — | — |
| 7KAT | Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore ring and SEC63 FN3 double… | electron microscopy | A | — | — |
| 7KAU | Cryo-EM structure of the Sec complex from S. cerevisiae, Sec61 pore ring and Sec63 FN3 double… | electron microscopy | A | — | 10 (best 0.72) |
| 7KAU | Cryo-EM structure of the sec complex from S. cerevisiae, SEC61 pore ring and SEC63 FN3 double… | electron microscopy | A | — | — |
| 7KB5 | Cryo-EM structure of the Sec complex from yeast, Sec63 FN3 and residues 210-216 mutated | electron microscopy | A | — | 8 (best 0.72) |
| 7KB5 | Cryo-EM structure of the sec complex from yeast, SEC63 FN3 and residues 210-216 mutated | electron microscopy | A | — | — |
| P32915 | AlphaFold monomer V2.0 prediction for protein transport protein SEC61 (P32915) | predicted | A | — | 7 (best 0.72) |
Experiment against prediction
- 6ND1 chain B against the predicted model P32915: TM-score 0.94, RMSD 2.01 Å
- 6ND1 chain B against the predicted model P32915: TM-score 0.94, RMSD 2.01 Å
- 7KB5 chain A against the predicted model P32915: TM-score 0.93, RMSD 2.06 Å
- 7KB5 chain A against the predicted model P32915: TM-score 0.93, RMSD 2.06 Å
- 6N3Q chain A against the predicted model P32915: TM-score 0.92, RMSD 2.31 Å
- 6N3Q chain A against the predicted model P32915: TM-score 0.92, RMSD 2.31 Å
- 7KAR chain A against the predicted model P32915: TM-score 0.92, RMSD 2.38 Å
- 7KAO chain A against the predicted model P32915: TM-score 0.91, RMSD 2.53 Å
- 7KAO chain A against the predicted model P32915: TM-score 0.91, RMSD 2.53 Å
- 7KAU chain A against the predicted model P32915: TM-score 0.91, RMSD 2.52 Å
Elsewhere
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