UniProt P32794
ATPase family gene 2 protein (P32794)
ATPase family gene 2 protein (UniProt P32794), EC 3.6.4.10: 4 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 60 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- P32794
- Protein
- ATPase family gene 2 protein
- EC
- 3.6.4.10
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 60 · 3 records with a druggable one
Structures
5 records of P32794 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7NKU | Diazaborine bound DRG1(AFG2) | electron microscopy | A, B, C, D, E, F | AGS, TDB | — |
| 7YKK | Cryo-EM structure of Drg1 hexamer treated with ADP | electron microscopy | D, E, F, A, B, C | ATP | 20 (best 0.84) |
| 7YKZ | Cryo-EM structure of Drg1 hexamer in the planar state treated with ADP/AMPPNP/Diazaborine | electron microscopy | D, F, B, E, A, C | ADP, ATP, NDT | 20 (best 0.82) |
| 7Z11 | Structure of substrate bound DRG1 (AFG2) | electron microscopy | A, B, C, D, E, F | AGS | 20 (best 0.84) |
| P32794 | AlphaFold monomer V2.0 prediction for ATPase family gene 2 protein (P32794) | predicted | A | — | — |
Ligands
- AGS · Phosphothiophosphoric acid-adenylate ester · in 2 records
- ATP · Adenosine-5'-triphosphate · in 2 records
- ADP · Adenosine-5'-diphosphate · in 1 record
- NDT · 2-(toluene-4-sulfonyl)-2H-benzo[d][1,2,3]diazaborinin-1-ol · in 1 record
- TDB · 6-methyl-2(propane-1-sulfonyl)-2H-thieno[3,2-D][1,2, 3]diazaborinin-1-ol · in 1 record
Experiment against prediction
- 7Z11 chain F against the predicted model P32794: TM-score 0.94, RMSD 2.40 Å
- 7Z11 chain D against the predicted model P32794: TM-score 0.90, RMSD 3.10 Å
- 7Z11 chain A against the predicted model P32794: TM-score 0.88, RMSD 3.59 Å
- 7Z11 chain C against the predicted model P32794: TM-score 0.87, RMSD 3.68 Å
- 7Z11 chain B against the predicted model P32794: TM-score 0.87, RMSD 3.71 Å
- 7Z11 chain E against the predicted model P32794: TM-score 0.81, RMSD 4.89 Å
- 7YKZ chain B against the predicted model P32794: TM-score 0.80, RMSD 4.64 Å
- 7YKZ chain E against the predicted model P32794: TM-score 0.79, RMSD 4.58 Å
- 7YKZ chain D against the predicted model P32794: TM-score 0.79, RMSD 4.73 Å
- 7YKK chain D against the predicted model P32794: TM-score 0.78, RMSD 4.84 Å
Elsewhere
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