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UniProt P32597

Nuclear protein STH1/NPS1 (P32597)

Nuclear protein STH1/NPS1 (UniProt P32597), EC 3.6.4.12: 26 experimental structures on GenesisL1, 3 ligands bound, 75 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
P32597
Protein
Nuclear protein STH1/NPS1
EC
3.6.4.12
Experimental structures
26
Predicted models
0
Ligands
3
Pockets
75 · 7 records with a druggable one

Structures

26 records of P32597 in the MolNFT archive: 26 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6K15RSC substrate-recruitment moduleelectron microscopyJ—10 (best 0.84)
6K15Rsc substrate-recruitment moduleelectron microscopyJ——
6KMBCrystal structure of Sth1 bromodomainx-ray diffractionA, B, C, D——
6KMBCrystal structure of STH1 bromodomainx-ray diffractionA, B, C, D——
6KMJCrystal structure of Sth1 bromodomain in complex with H3K14Acx-ray diffractionA——
6KMJCrystal structure of STH1 bromodomain in complex with H3K14ACx-ray diffractionA——
6KW3The ClassA RSC-Nucleosome Complexelectron microscopyW, J, Y—13 (best 0.87)
6KW3The classa rsc-nucleosome complexelectron microscopyW, J, Y——
6KW4The ClassB RSC-Nucleosome Complexelectron microscopyJ, V, Y—10 (best 0.86)
6KW4The classb rsc-nucleosome complexelectron microscopyJ, V, Y——
6KW5The ClassC RSC-Nucleosome Complexelectron microscopyJ, P, Q—13 (best 0.86)
6KW5The classc rsc-nucleosome complexelectron microscopyJ, P, Q——
6LQZSolution structure of Taf14ET-Sth1EBMCsolution nmrB——
6LQZSolution structure of TAF14ET-STH1EBMCsolution nmrB——
6MR4Crystal structure of the Sth1 bromodomain from S.cerevisiaex-ray diffractionA, B, C, D, E, F—9 (best 0.82)
6MR4Crystal structure of the STH1 bromodomain from S.CEREVISIAEx-ray diffractionA, B, C, D, E, F——
6TDAStructure of SWI/SNF chromatin remodeler rsc bound to a nucleosomeelectron microscopyS——
6UY1Crystal structure of the STH1 bromodomain from saccharomyces cerevisiae at 2.2 ångström resolutionx-ray diffractionA, B, C, D, E, F, G, HMG—
6V8ORSC coreelectron microscopyR—10 (best 0.86)
6V8ORSC COREelectron microscopyR——
6V92RSC-NCPelectron microscopyR—10 (best 0.88)
6V92RSC-NCPelectron microscopyR——
6VZ4Cryo-EM structure of STH1-ARP7-ARP9-RTT102 bound to the nucleosome in ADP beryllium fluoride stateelectron microscopyKMG, ADP, BEF—
6VZGCryo-EM structure of STH1-ARP7-ARP9-RTT102electron microscopyK——
7F3SCrystal structure of STH1 bromodomain in complex with H3K14BZ peptidex-ray diffractionA——
P32597AlphaFold monomer V2.0 prediction for nuclear protein STH1/NPS1 (P32597)———

Ligands

  • MG · Magnesium ion · in 2 records
  • ADP · Adenosine-5'-diphosphate · in 1 record
  • BEF · Beryllium trifluoride ion · in 1 record

Elsewhere

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