UniProt P32502
Translation initiation factor eIF-2B subunit beta (P32502)
Translation initiation factor eIF-2B subunit beta (UniProt P32502): 11 experimental structures and 1 predicted model on GenesisL1, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32502
- Protein
- Translation initiation factor eIF-2B subunit beta
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 31 · 3 records with a druggable one
Structures
12 records of P32502 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6I3M | EIF2B:EIF2 complex, phosphorylated on EIF2 alpha serine 52. | electron microscopy | E, F | — | — |
| 6I7T | EIF2B:EIF2 complex | electron microscopy | E, F | — | — |
| 6QG0 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 1) | electron microscopy | D, C | — | 10 (best 0.85) |
| 6QG0 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model 1) | electron microscopy | D, C | — | — |
| 6QG1 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2) | electron microscopy | D, C | — | 10 (best 0.87) |
| 6QG1 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model 2) | electron microscopy | D, C | — | — |
| 6QG2 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model a) | electron microscopy | C, D | — | — |
| 6QG3 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model B) | electron microscopy | C, D | — | — |
| 6QG5 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model C) | electron microscopy | C, D | — | 11 (best 0.87) |
| 6QG5 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model C) | electron microscopy | C, D | — | — |
| 6QG6 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model D) | electron microscopy | C, D | — | — |
| P32502 | AlphaFold monomer V2.0 prediction for translation initiation factor eif-2B subunit beta (P32502) | predicted | A | — | — |
Experiment against prediction
- 6I3M chain E against the predicted model P32502: TM-score 0.93, RMSD 1.57 Å
- 6I3M chain F against the predicted model P32502: TM-score 0.93, RMSD 1.57 Å
- 6I7T chain F against the predicted model P32502: TM-score 0.93, RMSD 1.72 Å
- 6I7T chain E against the predicted model P32502: TM-score 0.93, RMSD 1.72 Å
- 6QG1 chain C against the predicted model P32502: TM-score 0.92, RMSD 1.66 Å
- 6QG1 chain C against the predicted model P32502: TM-score 0.92, RMSD 1.66 Å
- 6QG0 chain C against the predicted model P32502: TM-score 0.92, RMSD 1.66 Å
- 6QG0 chain C against the predicted model P32502: TM-score 0.92, RMSD 1.66 Å
- 6QG0 chain D against the predicted model P32502: TM-score 0.92, RMSD 1.66 Å
- 6QG0 chain D against the predicted model P32502: TM-score 0.92, RMSD 1.66 Å
Elsewhere
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