UniProt P32501
Translation initiation factor eIF-2B subunit epsilon (P32501)
Translation initiation factor eIF-2B subunit epsilon (UniProt P32501): 18 experimental structures and 1 predicted model on GenesisL1, 57 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32501
- Protein
- Translation initiation factor eIF-2B subunit epsilon
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 57 · 8 records with a druggable one
Structures
19 records of P32501 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PAQ | Crystal structure of the catalytic fragment of eukaryotic initiation factor 2B epsilon | x-ray diffraction | A | — | — |
| 1PAQ | Crystal structure of the catalytic fragment of eukaryotic initiation factor 2B epsilon | x-ray diffraction | A | — | — |
| 6I3M | eIF2B:eIF2 complex, phosphorylated on eIF2 alpha serine 52. | electron microscopy | G, H | — | 3 (best 0.83) |
| 6I3M | EIF2B:EIF2 complex, phosphorylated on EIF2 alpha serine 52. | electron microscopy | G, H | — | — |
| 6I7T | eIF2B:eIF2 complex | electron microscopy | G, H | — | 6 (best 0.85) |
| 6I7T | EIF2B:EIF2 complex | electron microscopy | G, H | — | — |
| 6QG0 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 1) | electron microscopy | I, J | — | 9 (best 0.83) |
| 6QG0 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model 1) | electron microscopy | I, J | — | — |
| 6QG1 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model 2) | electron microscopy | I, J | — | 9 (best 0.87) |
| 6QG1 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model 2) | electron microscopy | I, J | — | — |
| 6QG2 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model A) | electron microscopy | I, J | — | 8 (best 0.87) |
| 6QG2 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model a) | electron microscopy | I, J | — | — |
| 6QG3 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model B) | electron microscopy | I, J | — | 6 (best 0.82) |
| 6QG3 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model B) | electron microscopy | I, J | — | — |
| 6QG5 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model C) | electron microscopy | I, J | — | 8 (best 0.84) |
| 6QG5 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model C) | electron microscopy | I, J | — | — |
| 6QG6 | Structure of eIF2B-eIF2 (phosphorylated at Ser51) complex (model D) | electron microscopy | I, J | — | 8 (best 0.88) |
| 6QG6 | Structure of EIF2B-EIF2 (phosphorylated at SER51) complex (model D) | electron microscopy | I, J | — | — |
| P32501 | AlphaFold monomer V2.0 prediction for translation initiation factor eif-2B subunit epsilon (P32501) | predicted | A | — | — |
Experiment against prediction
- 1PAQ chain A against the predicted model P32501: TM-score 0.97, RMSD 0.93 Å
- 1PAQ chain A against the predicted model P32501: TM-score 0.97, RMSD 0.93 Å
- 6I3M chain H against the predicted model P32501: TM-score 0.97, RMSD 1.45 Å
- 6I3M chain H against the predicted model P32501: TM-score 0.97, RMSD 1.45 Å
- 6I3M chain G against the predicted model P32501: TM-score 0.97, RMSD 1.45 Å
- 6I3M chain G against the predicted model P32501: TM-score 0.97, RMSD 1.45 Å
- 6I7T chain H against the predicted model P32501: TM-score 0.97, RMSD 1.47 Å
- 6I7T chain H against the predicted model P32501: TM-score 0.97, RMSD 1.47 Å
- 6I7T chain G against the predicted model P32501: TM-score 0.97, RMSD 1.47 Å
- 6I7T chain G against the predicted model P32501: TM-score 0.97, RMSD 1.47 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.