UniProt P32390
Actin-related protein 3 (P32390)
Actin-related protein 3 (UniProt P32390): 9 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 54 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32390
- Protein
- Actin-related protein 3
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 54 · 7 records with a druggable one
Structures
10 records of P32390 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3DWL | Crystal Structure of Fission Yeast Arp2/3 Complex Lacking the Arp2 Subunit | x-ray diffraction | A, B | ATP | 13 (best 0.75) |
| 3DWL | Crystal structure of fission yeast ARP2/3 complex lacking the ARP2 subunit | x-ray diffraction | A, B | ATP | 13 (best 0.75) |
| 6W17 | Structure of Dip1-activated Arp2/3 complex with nucleated actin filament | electron microscopy | A | MG, ATP | 4 (best 0.81) |
| 6W17 | Structure of DIP1-activated ARP2/3 complex with nucleated actin filament | electron microscopy | A | MG, ATP | — |
| 6W18 | Structure of S. pombe Arp2/3 complex in inactive state | electron microscopy | A | ATP | 9 (best 0.80) |
| 6W18 | Structure of S. pombe ARP2/3 complex in inactive state | electron microscopy | A | ATP | — |
| 8E9B | Cryo-EM structure of S. pombe Arp2/3 complex in the branch junction | electron microscopy | A | MG, ADP | 5 (best 0.82) |
| 8UXW | Arp2/3 branch junction complex, ADP state | electron microscopy | A | ADP, MG | 5 (best 0.78) |
| 8UXX | Arp2/3 branch junction complex, BeFx state | electron microscopy | A | ADP, MG, BEF | 5 (best 0.83) |
| P32390 | AlphaFold monomer V2.0 prediction for actin-related protein 3 (P32390) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6W17 chain A against the predicted model P32390: TM-score 0.95, RMSD 1.89 Å
- 6W17 chain A against the predicted model P32390: TM-score 0.95, RMSD 1.89 Å
- 3DWL chain B against the predicted model P32390: TM-score 0.92, RMSD 2.07 Å
- 3DWL chain B against the predicted model P32390: TM-score 0.92, RMSD 2.07 Å
- 3DWL chain A against the predicted model P32390: TM-score 0.92, RMSD 2.07 Å
- 3DWL chain A against the predicted model P32390: TM-score 0.92, RMSD 2.07 Å
- 6W18 chain A against the predicted model P32390: TM-score 0.92, RMSD 2.18 Å
- 6W18 chain A against the predicted model P32390: TM-score 0.92, RMSD 2.18 Å
- 8UXW chain A against the predicted model P32390: TM-score 0.91, RMSD 2.32 Å
- 8E9B chain A against the predicted model P32390: TM-score 0.91, RMSD 2.27 Å
Elsewhere
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