UniProt P32298
G protein-coupled receptor kinase 4 (P32298)
G protein-coupled receptor kinase 4 (UniProt P32298), EC 2.7.11.16: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 32 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P32298
- Protein
- G protein-coupled receptor kinase 4
- EC
- 2.7.11.16
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 32 · 2 records with a druggable one
Structures
3 records of P32298 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4YHJ | Structure and Function of the Hypertension Variant A486V of G Protein-coupled Receptor Kinase 4… | x-ray diffraction | A, B | AN2 | 16 (best 0.79) |
| 4YHJ | Structure and function of the hypertension variant A486V of G protein- coupled receptor kinase 4… | x-ray diffraction | A, B | AN2 | 16 (best 0.79) |
| P32298 | AlphaFold monomer V2.0 prediction for G protein-coupled receptor kinase 4 (P32298) | predicted | A | — | — |
Ligands
- AN2 · Amp phosphoramidate · in 2 records
Experiment against prediction
- 4YHJ chain B against the predicted model P32298: TM-score 0.98, RMSD 1.14 Å
- 4YHJ chain B against the predicted model P32298: TM-score 0.98, RMSD 1.14 Å
- 4YHJ chain A against the predicted model P32298: TM-score 0.97, RMSD 1.61 Å
- 4YHJ chain A against the predicted model P32298: TM-score 0.97, RMSD 1.61 Å
Elsewhere
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