UniProt P32248

C-C chemokine receptor type 7,Sialidase A,C-C chemokine receptor type 7 (P32248)

C-C chemokine receptor type 7,Sialidase A,C-C chemokine receptor type 7 (UniProt P32248), EC 3.2.1.18: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, druggability and…

UniProt: P32248
Protein: C-C chemokine receptor type 7,Sialidase A,C-C chemokine receptor type 7
EC: 3.2.1.18
Experimental structures: 2
Predicted models: 1
Ligands: 2
Pockets: 8 · 1 record with a druggable one

Structures

3 records of P32248 in the MolNFT archive: 2 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6QZH	Structure of the human CC Chemokine Receptor 7 in complex with the intracellular allosteric…	x-ray diffraction	A	JLW, NA	8 (best 0.72)
6QZH	Structure of the human cc chemokine receptor 7 in complex with the intracellular allosteric…	x-ray diffraction	A	JLW, NA	—
P32248	AlphaFold monomer V2.0 prediction for C-C chemokine receptor type 7 (P32248)	predicted	A	—	—

Ligands

JLW · 3-[[4-[[(1~{R})-2,2-dimethyl-1-(5-methylfuran-2-yl) propyl]amino]-1,1-bis(oxidanylidene)-1,2,5-thiadiazol-3-yl]amino]-~{N},~{N},6-trimethyl-2-oxidanyl-benzamide · in 2 records
NA · Sodium ion · in 2 records

Experiment against prediction

6QZH chain A against the predicted model P32248: TM-score 0.36, RMSD 2.07 Å
6QZH chain A against the predicted model P32248: TM-score 0.36, RMSD 2.07 Å
6QZH chain A against the predicted model P62575: TM-score 0.65, RMSD 2.12 Å
6QZH chain A against the predicted model P62575: TM-score 0.65, RMSD 2.12 Å

Elsewhere

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