UniProt P32120
Beta-arrestin-2 (P32120)
Beta-arrestin-2 (UniProt P32120): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 80 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P32120
- Protein
- Beta-arrestin-2
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 80 · 6 records with a druggable one
Structures
9 records of P32120 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3P2D | Crystal structure of arrestin-3 reveals the basis of the difference in receptor binding between two… | x-ray diffraction | A, B | — | — |
| 5TV1 | active arrestin-3 with inositol hexakisphosphate | x-ray diffraction | A | IHP | 6 (best 0.51) |
| 5TV1 | Active arrestin-3 with inositol hexakisphosphate | x-ray diffraction | A | IHP | — |
| 8GO9 | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Atypical… | electron microscopy | A, F | — | 14 (best 0.80) |
| 8GOC | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Vasopressin… | electron microscopy | A, B, C | — | 12 (best 0.72) |
| 8GOO | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human C5a… | electron microscopy | A, B, C | — | 13 (best 0.78) |
| 8I10 | Structure of beta-arrestin2 in complex with a phosphopeptide corresponding to the human Vasopressin… | electron microscopy | A, B, C | — | 17 (best 0.69) |
| 8J8R | Structure of beta-arrestin2 in complex with M2Rpp | electron microscopy | A, B, C | — | 18 (best 0.76) |
| P32120 | AlphaFold monomer V2.0 prediction for beta-arrestin-2 (P32120) | predicted | A | — | — |
Ligands
- IHP · Inositol hexakisphosphate · in 2 records
Experiment against prediction
- 5TV1 chain A against the predicted model P32120: TM-score 0.94, RMSD 2.04 Å
- 5TV1 chain A against the predicted model P32120: TM-score 0.94, RMSD 2.04 Å
- 3P2D chain B against the predicted model P32120: TM-score 0.91, RMSD 2.09 Å
- 3P2D chain A against the predicted model P32120: TM-score 0.91, RMSD 2.17 Å
- 8J8R chain B against the predicted model P32120: TM-score 0.89, RMSD 2.44 Å
- 8GOC chain A against the predicted model P32120: TM-score 0.88, RMSD 2.48 Å
- 8GOC chain B against the predicted model P32120: TM-score 0.88, RMSD 2.48 Å
- 8GOC chain C against the predicted model P32120: TM-score 0.88, RMSD 2.50 Å
- 8J8R chain C against the predicted model P32120: TM-score 0.88, RMSD 2.47 Å
- 8GOO chain C against the predicted model P32120: TM-score 0.88, RMSD 2.49 Å
Elsewhere
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