UniProt P32019
Type II inositol 1,4,5-trisphosphate 5-phosphatase (P32019)
Type II inositol 1,4,5-trisphosphate 5-phosphatase (UniProt P32019), EC 3.1.3.36: 10 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 6 pockets. Binding sites, druggability and experiment against…
- UniProt
- P32019
- Protein
- Type II inositol 1,4,5-trisphosphate 5-phosphatase
- EC
- 3.1.3.36
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 6 · 0 records with a druggable one
Structures
11 records of P32019 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3MTC | Crystal Structure of INPP5B in complex with phosphatidylinositol 4-phosphate | x-ray diffraction | A | — | — |
| 3MTC | Crystal structure of INPP5B in complex with phosphatidylinositol 4- phosphate | x-ray diffraction | A | — | — |
| 3N9V | Crystal Structure of INPP5B | x-ray diffraction | A, B | — | — |
| 3N9V | Crystal structure of INPP5B | x-ray diffraction | A, B | — | — |
| 4CML | Crystal Structure of INPP5B in complex with Phosphatidylinositol 3,4- bisphosphate | x-ray diffraction | A | — | — |
| 4CML | Crystal structure of INPP5B in complex with phosphatidylinositol 3,4- bisphosphate | x-ray diffraction | A | — | — |
| 5A7I | Crystal structure of INPP5B in complex with biphenyl 3,3',4,4',5,5'- hexakisphosphate | x-ray diffraction | A | B6K, PO4, CL | 1 (best 0.41) |
| 5A7I | Crystal structure of INPP5B in complex with biphenyl 3,3',4, 4',5,5'-hexakisphosphate | x-ray diffraction | A | — | — |
| 5A7J | Crystal structure of INPP5B in complex with benzene 1,2,4,5- tetrakisphosphate | x-ray diffraction | A, B | SO4, K2Y | 5 (best 0.50) |
| 5A7J | Crystal structure of INPP5B in complex with benzene 1,2,4,5- tetrakisphosphate | x-ray diffraction | A, B | — | — |
| P32019 | AlphaFold monomer V2.0 prediction for type II inositol 1,4,5-trisphosphate 5-phosphatase (P32019) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3N9V chain B against the predicted model P32019: TM-score 1.00, RMSD 0.44 Å
- 3N9V chain B against the predicted model P32019: TM-score 1.00, RMSD 0.44 Å
- 3N9V chain A against the predicted model P32019: TM-score 0.99, RMSD 0.54 Å
- 3N9V chain A against the predicted model P32019: TM-score 0.99, RMSD 0.54 Å
- 3MTC chain A against the predicted model P32019: TM-score 0.99, RMSD 0.82 Å
- 3MTC chain A against the predicted model P32019: TM-score 0.99, RMSD 0.82 Å
- 4CML chain A against the predicted model P32019: TM-score 0.99, RMSD 0.82 Å
- 4CML chain A against the predicted model P32019: TM-score 0.99, RMSD 0.82 Å
- 5A7J chain A against the predicted model P32019: TM-score 0.99, RMSD 0.76 Å
- 5A7J chain A against the predicted model P32019: TM-score 0.99, RMSD 0.76 Å
Elsewhere
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