UniProt P31213
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (P31213)
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (UniProt P31213), EC 1.3.1.22: 3 experimental structures on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P31213
- Protein
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2
- EC
- 1.3.1.22
- Experimental structures
- 3
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 1 · 1 record with a druggable one
Structures
3 records of P31213 in the MolNFT archive: 3 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7BW1 | Crystal structure of Steroid 5-alpha-reductase 2 in complex with Finasteride | x-ray diffraction | A | NDX, SO4 | 1 (best 0.86) |
| 7BW1 | Crystal structure of steroid 5-alpha-reductase 2 in complex with finasteride | x-ray diffraction | A | NDX, SO4 | — |
| P31213 | AlphaFold monomer V2.0 prediction for 3-oxo-5-alpha-steroid 4-dehydrogenase 2 (P31213) | — | — | — |
Ligands
- NDX · [[(2~{R},3~{S},4~{R},5~{R})-5-[4-[(1~{S},3~{A}~{S}, 3~{B}~{S},5~{A}~{R},8~{S},9~{A}~{R},9~{B}~{S}, 11~{A}~{S})-1-(~{tert}-butylcarbamoyl)-9~{A},11~{A}-dimethyl-7-oxidanylidene-1,2,3,3~{A},3~{B},4,5,5~{A}, 6,8,9,9~{B},10,11-tetradecahydroindeno[5,4-f]quinolin-8-yl]-3-aminocarbonyl-4~{H}-pyridin-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3-oxidanyl-4-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate · in 2 records
- SO4 · Sulfate ion · in 2 records
Elsewhere
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