UniProt P30876
DNA-directed RNA polymerase II subunit RPB2 (P30876)
DNA-directed RNA polymerase II subunit RPB2 (UniProt P30876), EC 2.7.7.6: 19 experimental structures on GenesisL1, 2 ligands bound, 59 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P30876
- Protein
- DNA-directed RNA polymerase II subunit RPB2
- EC
- 2.7.7.6
- Experimental structures
- 19
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 59 · 4 records with a druggable one
Structures
19 records of P30876 in the MolNFT archive: 19 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5IY6 | Human holo-PIC in the closed state | electron microscopy | B | MG, ZN | 14 (best 0.88) |
| 5IY6 | Human holo-pic in the closed state | electron microscopy | B | — | — |
| 5IY7 | Human holo-pic in the open state | electron microscopy | B | — | — |
| 5IY8 | Human holo-pic in the initial transcribing state | electron microscopy | B | — | — |
| 5IY9 | Human holo-PIC in the initial transcribing state (no IIS) | electron microscopy | B | ZN | — |
| 5IY9 | Human holo-pic in the initial transcribing state (no iis) | electron microscopy | B | — | — |
| 5IYA | Human core-PIC in the closed state | electron microscopy | B | MG, ZN | — |
| 5IYA | Human core-pic in the closed state | electron microscopy | B | — | — |
| 5IYB | Human core-PIC in the open state | electron microscopy | B | ZN, MG | 16 (best 0.87) |
| 5IYB | Human core-pic in the open state | electron microscopy | B | — | — |
| 5IYC | Human core-PIC in the initial transcribing state | electron microscopy | B | MG, ZN | 17 (best 0.91) |
| 5IYC | Human core-pic in the initial transcribing state | electron microscopy | B | — | — |
| 5IYD | Human core-PIC in the initial transcribing state (no IIS) | electron microscopy | B | MG, ZN | — |
| 5IYD | Human core-pic in the initial transcribing state (no iis) | electron microscopy | B | — | — |
| 6DRD | RNA Pol II(G) | electron microscopy | B | — | 12 (best 0.87) |
| 6DRD | RNA pol II(G) | electron microscopy | B | — | — |
| 6O9L | Human holo-pic in the closed state | electron microscopy | B | ZN, MG | — |
| 6XRE | Structure of the P53/RNA polymerase II assembly | electron microscopy | B | ZN | — |
| P30876 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase II subunit RPB2 (P30876) | — | — | — |
Ligands
Elsewhere
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