UniProt P30429
Cell death protein 4 (P30429)
Cell death protein 4 (UniProt P30429): 16 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P30429
- Protein
- Cell death protein 4
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 36 · 2 records with a druggable one
Structures
17 records of P30429 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2A5Y | Structure of a CED-4/CED-9 complex | x-ray diffraction | B, C | — | — |
| 2A5Y | Structure of a ced-4/CED-9 complex | x-ray diffraction | B, C | — | — |
| 3LQQ | Structure of the CED-4 Apoptosome | x-ray diffraction | A, B | — | — |
| 3LQQ | Structure of the ced-4 apoptosome | x-ray diffraction | A, B | — | — |
| 3LQR | Structure of CED-4:CED-3 complex | x-ray diffraction | A, B | — | — |
| 3LQR | Structure of ced-4:CED-3 complex | x-ray diffraction | A, B | — | — |
| 4M9S | crystal structure of CED-4 bound CED-3 fragment | x-ray diffraction | A, B, C, D | — | — |
| 4M9S | Crystal structure of ced-4 bound ced-3 fragment | x-ray diffraction | A, B, C, D | — | — |
| 4M9X | Crystal structure of CED-4 bound CED-3 fragment | x-ray diffraction | A, B | — | — |
| 4M9X | Crystal structure of ced-4 bound ced-3 fragment | x-ray diffraction | A, B | — | — |
| 4M9Y | Crystal structure of CED-4 bound CED-3 fragment | x-ray diffraction | A, B | — | — |
| 4M9Y | Crystal structure of ced-4 bound ced-3 fragment | x-ray diffraction | A, B | — | — |
| 4M9Z | Crystal structure of CED-4 bound CED-3 fragment | x-ray diffraction | A, B, C, D | — | — |
| 4M9Z | Crystal structure of ced-4 bound ced-3 fragment | x-ray diffraction | A, B, C, D | — | — |
| 8JNS | cryo-EM structure of a CED-4 hexamer | electron microscopy | A, B, C, D, E, F, G, H, I | MG, ATP | 20 (best 0.83) |
| 8JOL | cryo-EM structure of the CED-4/CED-3 holoenzyme | electron microscopy | A, B | MG, ATP | 16 (best 0.82) |
| P30429 | AlphaFold monomer V2.0 prediction for cell death protein 4 (P30429) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8JNS chain F against the predicted model P30429: TM-score 0.98, RMSD 0.99 Å
- 8JNS chain E against the predicted model P30429: TM-score 0.98, RMSD 0.99 Å
- 8JNS chain D against the predicted model P30429: TM-score 0.98, RMSD 1.00 Å
- 2A5Y chain C against the predicted model P30429: TM-score 0.98, RMSD 1.25 Å
- 2A5Y chain C against the predicted model P30429: TM-score 0.98, RMSD 1.25 Å
- 4M9Z chain B against the predicted model P30429: TM-score 0.97, RMSD 1.49 Å
- 4M9Z chain B against the predicted model P30429: TM-score 0.97, RMSD 1.49 Å
- 4M9Z chain D against the predicted model P30429: TM-score 0.97, RMSD 1.51 Å
- 4M9Z chain D against the predicted model P30429: TM-score 0.97, RMSD 1.51 Å
- 4M9X chain B against the predicted model P30429: TM-score 0.97, RMSD 1.53 Å
Elsewhere
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