UniProt P30304
M-phase inducer phosphatase 1 (P30304)
M-phase inducer phosphatase 1 (UniProt P30304), EC 3.1.3.48: 3 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P30304
- Protein
- M-phase inducer phosphatase 1
- EC
- 3.1.3.48
- Experimental structures
- 3
- Predicted models
- 1
- Pockets
- 12 · 2 records with a druggable one
Structures
4 records of P30304 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1C25 | Human CDC25A catalytic domain | x-ray diffraction | A | — | — |
| 1C25 | Human CDC25A catalytic domain | x-ray diffraction | A | — | — |
| 8ROZ | Cryo-EM structure of CDK2-cyclin A in complex with CDC25A | electron microscopy | C | — | 9 (best 0.69) |
| P30304 | AlphaFold monomer V2.0 prediction for M-phase inducer phosphatase 1 (P30304) | predicted | A | — | 3 (best 0.55) |
Experiment against prediction
- 8ROZ chain C against the predicted model P30304: TM-score 0.94, RMSD 1.71 Å
- 1C25 chain A against the predicted model P30304: TM-score 0.94, RMSD 1.21 Å
- 1C25 chain A against the predicted model P30304: TM-score 0.94, RMSD 1.21 Å
Elsewhere
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