UniProt P30047
GTP cyclohydrolase 1 feedback regulatory protein (P30047)
GTP cyclohydrolase 1 feedback regulatory protein (UniProt P30047): 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 32 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P30047
- Protein
- GTP cyclohydrolase 1 feedback regulatory protein
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 32 · 3 records with a druggable one
Structures
11 records of P30047 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6Z80 | stimulatory human GTP cyclohydrolase I - GFRP complex | electron microscopy | L, K, N, M, O, P, Q, R, S, T | PHE | 10 (best 0.83) |
| 6Z80 | Stimulatory human GTP cyclohydrolase I - gfrp complex | electron microscopy | L, K, N, M, O, P, Q, R, S, T | — | — |
| 6Z85 | Inhibitory human GTP cyclohydrolase I - gfrp complex | electron microscopy | K, L, M, N, O, P, Q, R, S, T | — | — |
| 7ACC | human GTP cyclohydrolase I feedback regulatory protein (GFRP) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | K | 11 (best 0.85) |
| 7ACC | Human GTP cyclohydrolase I feedback regulatory protein (gfrp) | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | K | — |
| 7AL9 | human GTP cyclohydrolase I feedback regulatory protein (GFRP) in complex with phenylalanine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | K, PHE | 11 (best 0.82) |
| 7AL9 | Human GTP cyclohydrolase I feedback regulatory protein (gfrp) in complex with phenylalanine | x-ray diffraction | A, B, C, D, E, F, G, H, I, J | K | — |
| 7ALB | Human gch-gfrp stimulatory complex 7-deaza-GTP bound | x-ray diffraction | a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t | — | — |
| 7ALC | Human gch-gfrp stimulatory complex | x-ray diffraction | F, G, H, I, J | — | — |
| 7ALQ | Human gch-gfrp inhibitory complex 7-deaza-GTP bound | x-ray diffraction | a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t | K | — |
| P30047 | AlphaFold monomer V2.0 prediction for GTP cyclohydrolase 1 feedback regulatory protein (P30047) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7ALQ chain r against the predicted model P30047: TM-score 0.99, RMSD 0.30 Å
- 7ALQ chain a against the predicted model P30047: TM-score 0.99, RMSD 0.30 Å
- 7ALQ chain q against the predicted model P30047: TM-score 0.99, RMSD 0.30 Å
- 7ALQ chain t against the predicted model P30047: TM-score 0.99, RMSD 0.30 Å
- 7ALQ chain e against the predicted model P30047: TM-score 0.99, RMSD 0.30 Å
- 7ALQ chain j against the predicted model P30047: TM-score 0.99, RMSD 0.30 Å
- 7ALQ chain f against the predicted model P30047: TM-score 0.99, RMSD 0.30 Å
- 7ALQ chain i against the predicted model P30047: TM-score 0.99, RMSD 0.31 Å
- 7ALQ chain n against the predicted model P30047: TM-score 0.99, RMSD 0.31 Å
- 7ALQ chain h against the predicted model P30047: TM-score 0.99, RMSD 0.31 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.