UniProt P28702
Retinoic acid receptor RXR-beta (P28702)
Retinoic acid receptor RXR-beta (UniProt P28702): 14 experimental structures on GenesisL1, 2 ligands bound, 34 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- P28702
- Protein
- Retinoic acid receptor RXR-beta
- Experimental structures
- 14
- Predicted models
- 0
- Ligands
- 2
- Pockets
- 34 · 3 records with a druggable one
Structures
14 records of P28702 in the MolNFT archive: 14 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H9U | The structure of the human retinoid-X-receptor beta ligand binding domain in complex with the… | x-ray diffraction | A, B, C, D | — | — |
| 1H9U | The structure of the human retinoid-X-receptor beta ligand binding domain in complex with the… | x-ray diffraction | A, B, C, D | — | — |
| 1UHL | Crystal structure of the LXRalfa-RXRbeta LBD heterodimer | x-ray diffraction | A | — | — |
| 1UHL | Crystal structure of the lxralfa-rxrbeta lbd heterodimer | x-ray diffraction | A | — | — |
| 5HJP | Identification of LXRbeta selective agonists for the treatment of Alzheimer's Disease | x-ray diffraction | A, C | — | 11 (best 0.84) |
| 5HJP | Identification of lxrbeta selective agonists for the treatment of ALZHEIMER'S disease | x-ray diffraction | A, C | — | — |
| 5I4V | Discovery of novel, orally efficacious Liver X Receptor (LXR) beta agonists | x-ray diffraction | B, F | — | 11 (best 0.82) |
| 5I4V | Discovery of novel, orally efficacious liver X receptor (lxr) beta agonists | x-ray diffraction | B, F | — | — |
| 5KYA | Brain penetrant liver X receptor (LXR) modulators based on a… | x-ray diffraction | B, F | — | 12 (best 0.81) |
| 5KYA | Brain penetrant liver X receptor (lxr) modulators based on a 2,4,5,6… | x-ray diffraction | B, F | — | — |
| 5KYJ | Brain penetrant liver X receptor (LXR) modulators based on a… | x-ray diffraction | B, F | — | — |
| 5KYJ | Brain penetrant liver X receptor (lxr) modulators based on a 2,4,5,6… | x-ray diffraction | B, F | — | — |
| 7A78 | Crystal structure of rxr beta lbd in complexes with palmitic acid and grip-1 peptide | x-ray diffraction | A | PLM, CL | — |
| P28702 | AlphaFold monomer V2.0 prediction for retinoic acid receptor rxr-beta (P28702) | — | — | — |
Ligands
Experiment against prediction
- 5I4V chain F against the predicted model Q15596: TM-score 0.27, RMSD 5.02 Å
- 5I4V chain B against the predicted model Q15596: TM-score 0.27, RMSD 4.87 Å
Elsewhere
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