UniProt P28630
DNA polymerase III subunit delta (P28630)
DNA polymerase III subunit delta (UniProt P28630), EC 2.7.7.7: 32 experimental structures and 1 predicted model on GenesisL1, 128 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P28630
- Protein
- DNA polymerase III subunit delta
- EC
- 2.7.7.7
- Experimental structures
- 32
- Predicted models
- 1
- Pockets
- 128 · 19 records with a druggable one
Structures
33 records of P28630 in the MolNFT archive: 32 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1JQJ | Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of… | x-ray diffraction | C, D | — | 11 (best 0.49) |
| 1JQJ | Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of… | x-ray diffraction | C, D | — | — |
| 1JQL | Mechanism of Processivity Clamp Opening by the Delta Subunit Wrench of the Clamp Loader Complex of… | x-ray diffraction | B | — | 1 (best 0.52) |
| 1JQL | Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of… | x-ray diffraction | B | — | — |
| 1JR3 | Crystal Structure of the Processivity Clamp Loader Gamma Complex of E. coli DNA Polymerase III | x-ray diffraction | D | — | 6 (best 0.73) |
| 1JR3 | Crystal structure of the processivity clamp loader gamma complex of E. COLI DNA polymerase III | x-ray diffraction | D | — | — |
| 1XXH | ATPgS Bound E. Coli Clamp Loader Complex | x-ray diffraction | A, F | — | 7 (best 0.77) |
| 1XXH | Atpgs bound E. COLI clamp loader complex | x-ray diffraction | A, F | — | — |
| 1XXI | ADP Bound E. coli Clamp Loader Complex | x-ray diffraction | A, F | — | 7 (best 0.77) |
| 1XXI | ADP bound E. COLI clamp loader complex | x-ray diffraction | A, F | — | — |
| 3GLF | Crystal Structure of the Ecoli Clamp Loader Bound to Primer-Template DNA | x-ray diffraction | A, F | — | — |
| 3GLF | Crystal structure of the ecoli clamp loader bound to primer-template DNA | x-ray diffraction | A, F | — | — |
| 3GLG | Crystal Structure of a Mutant (gammaT157A) E. coli Clamp Loader Bound to Primer-Template DNA | x-ray diffraction | A, F | — | — |
| 3GLG | Crystal structure of a mutant (GAMMAT157A) E. COLI clamp loader bound to primer-template DNA | x-ray diffraction | A, F | — | — |
| 3GLH | Crystal Structure of the E. coli clamp loader bound to Psi Peptide | x-ray diffraction | A, F, K | — | — |
| 3GLH | Crystal structure of the E. COLI clamp loader bound to psi peptide | x-ray diffraction | A, F, K | — | — |
| 3GLI | Crystal Structure of the E. coli clamp loader bound to Primer-Template DNA and Psi Peptide | x-ray diffraction | A, F | — | — |
| 3GLI | Crystal structure of the E. COLI clamp loader bound to primer-template DNA and psi peptide | x-ray diffraction | A, F | — | — |
| 8GIY | E. coli clamp loader with closed clamp | electron microscopy | A | — | 7 (best 0.79) |
| 8GIZ | E. coli clamp loader with open clamp | electron microscopy | A | — | 6 (best 0.78) |
| 8GJ0 | E. coli clamp loader with open clamp on primed template DNA (form 1) | electron microscopy | A | — | 7 (best 0.79) |
| 8GJ1 | E. coli clamp loader with open clamp on primed template DNA (form 2) | electron microscopy | A | — | 6 (best 0.79) |
| 8GJ2 | E. coli clamp loader with closed clamp on primed template DNA | electron microscopy | A | — | 7 (best 0.83) |
| 8GJ3 | E. coli clamp loader on primed template DNA | electron microscopy | A | — | 7 (best 0.81) |
| 8VAL | Structure of the E. coli clamp loader bound to the beta clamp in a Open-DNAp/t conformation | electron microscopy | A | — | 6 (best 0.80) |
| 8VAM | Structure of the E. coli clamp loader bound to the beta clamp in a Semi-Open conformation | electron microscopy | A | — | 7 (best 0.76) |
| 8VAN | Structure of the E. coli clamp loader bound to the beta clamp in an Initial-Binding conformation | electron microscopy | A | — | 6 (best 0.61) |
| 8VAP | Structure of the E. coli clamp loader bound to the beta clamp in a Fully-Open conformation | electron microscopy | A | — | 7 (best 0.69) |
| 8VAQ | Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA1 conformation | electron microscopy | A | — | 6 (best 0.85) |
| 8VAR | Structure of the E. coli clamp loader bound to the beta clamp in a Closed-DNA2 conformation | electron microscopy | A | — | 6 (best 0.82) |
| 8VAS | Structure of the E. coli clamp loader bound to the beta clamp in an Altered-Collar conformation | electron microscopy | A | — | 7 (best 0.84) |
| 8VAT | Structure of the E. coli clamp loader bound to the beta clamp in a Open-RNAp/t conformation | electron microscopy | A | — | 8 (best 0.75) |
| P28630 | AlphaFold monomer V2.0 prediction for DNA polymerase III subunit delta (P28630) | predicted | A | — | 3 (best 0.52) |
Experiment against prediction
- 3GLF chain A against the predicted model P28630: TM-score 0.97, RMSD 1.05 Å
- 3GLF chain A against the predicted model P28630: TM-score 0.97, RMSD 1.05 Å
- 3GLG chain A against the predicted model P28630: TM-score 0.97, RMSD 1.06 Å
- 3GLG chain A against the predicted model P28630: TM-score 0.97, RMSD 1.06 Å
- 3GLI chain F against the predicted model P28630: TM-score 0.97, RMSD 1.07 Å
- 3GLI chain F against the predicted model P28630: TM-score 0.97, RMSD 1.07 Å
- 3GLI chain A against the predicted model P28630: TM-score 0.97, RMSD 1.08 Å
- 3GLI chain A against the predicted model P28630: TM-score 0.97, RMSD 1.08 Å
- 1JQL chain B against the predicted model P28630: TM-score 0.96, RMSD 0.93 Å
- 1JQL chain B against the predicted model P28630: TM-score 0.96, RMSD 0.93 Å
Elsewhere
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