UniProt P28068
HLA class II histocompatibility antigen, DM beta chain (P28068)
HLA class II histocompatibility antigen, DM beta chain (UniProt P28068): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- P28068
- Protein
- HLA class II histocompatibility antigen, DM beta chain
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 1 record with a druggable one
Structures
9 records of P28068 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HDM | Histocompatibility antigen HLA-dm | x-ray diffraction | B | — | — |
| 1HDM | Histocompatibility antigen HLA-dm | x-ray diffraction | B | — | — |
| 4FQX | Crystal structure of HLA-DM bound to HLA-DR1 | x-ray diffraction | D | — | — |
| 4FQX | Crystal structure of HLA-dm bound to HLA-DR1 | x-ray diffraction | D | — | — |
| 4GBX | Crystal structure of an immune complex at pH 6.5 | x-ray diffraction | D | — | — |
| 4GBX | Crystal structure of an immune complex at pH 6.5 | x-ray diffraction | D | — | — |
| 4I0P | HLA-DO in complex with HLA-DM | x-ray diffraction | B, F | NAG | 10 (best 0.78) |
| 4I0P | HLA-do in complex with HLA-dm | x-ray diffraction | B, F | — | — |
| P28068 | AlphaFold monomer V2.0 prediction for HLA class II histocompatibility antigen, dm beta chain… | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record
Experiment against prediction
- 1HDM chain B against the predicted model P28068: TM-score 0.95, RMSD 1.42 Å
- 1HDM chain B against the predicted model P28068: TM-score 0.95, RMSD 1.42 Å
- 4GBX chain D against the predicted model P28068: TM-score 0.93, RMSD 1.42 Å
- 4GBX chain D against the predicted model P28068: TM-score 0.93, RMSD 1.42 Å
- 4FQX chain D against the predicted model P28068: TM-score 0.93, RMSD 1.44 Å
- 4FQX chain D against the predicted model P28068: TM-score 0.93, RMSD 1.44 Å
- 4I0P chain F against the predicted model P28068: TM-score 0.92, RMSD 1.49 Å
- 4I0P chain F against the predicted model P28068: TM-score 0.92, RMSD 1.49 Å
- 4I0P chain B against the predicted model P28068: TM-score 0.91, RMSD 1.59 Å
- 4I0P chain B against the predicted model P28068: TM-score 0.91, RMSD 1.59 Å
Elsewhere
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