UniProt P28061
Proteasome subunit beta (P28061)
Proteasome subunit beta (UniProt P28061), EC 3.4.25.1: 34 experimental structures and 1 predicted model on GenesisL1, 59 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P28061
- Protein
- Proteasome subunit beta
- EC
- 3.4.25.1
- Experimental structures
- 34
- Predicted models
- 1
- Pockets
- 59 · 3 records with a druggable one
Structures
35 records of P28061 in the MolNFT archive: 34 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1PMA | Proteasome from thermoplasma acidophilum | x-ray diffraction | B, P, Q, R, S, T, U, V, W, X, Y, Z, 1, 2 | — | — |
| 1PMA | Proteasome from thermoplasma acidophilum | x-ray diffraction | B, P, Q, R, S, T, U, V, W, X, Y, Z, 1, 2 | — | — |
| 1YA7 | Implications for interactions of proteasome with PAN and PA700 from the 1.9 A structure of a… | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 1YA7 | Implications for interactions of proteasome with pan and PA700 from the 1.9 a structure of a… | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 1YAR | Structure of Archeabacterial 20S proteasome mutant D9S- PA26 complex | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 1YAR | Structure of archeabacterial 20S proteasome mutant D9S- PA26 complex | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 1YAU | Structure of Archeabacterial 20S proteasome- PA26 complex | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 1YAU | Structure of archeabacterial 20S proteasome- PA26 complex | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 3C91 | Thermoplasma acidophilum 20S proteasome with an open gate | electron microscopy | H, I, J, K, L, M, N, V, W, X, Y, Z, 1, 2 | — | — |
| 3C91 | Thermoplasma acidophilum 20S proteasome with an open gate | electron microscopy | H, I, J, K, L, M, N, V, W, X, Y, Z, 1, 2 | — | — |
| 3C92 | Thermoplasma acidophilum 20S proteasome with a closed gate | electron microscopy | H, I, J, K, L, M, N, V, W, X, Y, Z, 1, 2 | — | — |
| 3C92 | Thermoplasma acidophilum 20S proteasome with a closed gate | electron microscopy | H, I, J, K, L, M, N, V, W, X, Y, Z, 1, 2 | — | — |
| 3IPM | Crystal Structure of Archaeal 20S Proteasome in Complex with the C-terminus of PAN | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 3IPM | Crystal structure of archaeal 20S proteasome in complex with the C- terminus of pan | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 3J9I | Thermoplasma acidophilum 20S proteasome | electron microscopy | Z, M, 1, N, 2, H, V, I, W, J, X, K, Y, L | — | — |
| 3J9I | Thermoplasma acidophilum 20S proteasome | electron microscopy | Z, M, 1, N, 2, H, V, I, W, J, X, K, Y, L | — | — |
| 3JRM | Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 3JRM | Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 3JSE | Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 3JSE | Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 3JTL | Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 3JTL | Crystal structure of archaeal 20S proteasome in complex with mutated P26 activator | x-ray diffraction | H, I, J, K, L, M, N | — | — |
| 5VY3 | Thermoplasma acidophilum 20S proteasome using 200KEV with stage position | electron microscopy | B, D, F, H, J, L, N, P, R, T, V, X, Z, 1 | — | — |
| 5VY4 | Thermoplasma acidophilum 20S Proteasome using 200keV with image shift | electron microscopy | B, D, F, H, J, L, N, P, R, T, V, X, Z, 1 | — | — |
| 5VY4 | Thermoplasma acidophilum 20S proteasome using 200KEV with image shift | electron microscopy | B, D, F, H, J, L, N, P, R, T, V, X, Z, 1 | — | — |
| 6BDF | 2.8 a resolution reconstruction of the thermoplasma acidophilum 20S proteasome using cryo-electron… | electron microscopy | B, D, F, H, J, L, N, P, R, T, V, X, Z, 1 | — | — |
| 6UTF | Allosteric coupling between alpha-rings of the 20S proteasome, archaea 20S proteasome singly capped… | electron microscopy | Z, M, 1, N, 2, H, V, I, W, J, X, K, Y, L | — | — |
| 6UTG | Allosteric coupling between alpha-rings of the 20S proteasome, 20S singly capped with a PA26/V230F | electron microscopy | 1, 2, H, I, J, K, L, M, N, V, W, X, Y, Z | — | 18 (best 0.83) |
| 6UTG | Allosteric coupling between alpha-rings of the 20S proteasome, 20S singly capped with a PA26/V230F | electron microscopy | 1, 2, H, I, J, K, L, M, N, V, W, X, Y, Z | — | — |
| 6UTH | Allosteric coupling between alpha-rings of 20S proteasome, 20S proteasome singly capped with a… | electron microscopy | Z, M, 1, N, 2, H, V, I, W, J, X, K, Y, L | — | — |
| 6UTI | Allosteric coupling between alpha-rings of 20S proteasome, 20S proteasome with singly capped pan… | electron microscopy | H, I, J, K, L, M, N, V, W, X, Y, Z, a, b | — | — |
| 6UTJ | Allosteric couple between alpha rings of the 20S proteasome. 20S proteasome singly capped by… | electron microscopy | Z, M, 1, N, 2, H, V, I, W, J, X, K, Y, L | — | — |
| 8F66 | Thermoplasma acidophilum 20S proteasome - L81Y mutation in alpha subunit | electron microscopy | H, I, J, K, L, M, N, V, W, X, Y, Z, a, b | — | 20 (best 0.77) |
| 8F6A | Thermoplasma acidophilum 20S proteasome - wild type | electron microscopy | H, I, J, K, L, M, N, V, W, X, Y, Z, a, b | — | 20 (best 0.77) |
| P28061 | AlphaFold monomer V2.0 prediction for proteasome subunit beta (P28061) | predicted | A | — | 1 (best 0.27) |
Experiment against prediction
- 1YA7 chain H against the predicted model P28061: TM-score 0.99, RMSD 0.41 Å
- 1YA7 chain H against the predicted model P28061: TM-score 0.99, RMSD 0.41 Å
- 3JSE chain H against the predicted model P28061: TM-score 0.99, RMSD 0.42 Å
- 3JSE chain H against the predicted model P28061: TM-score 0.99, RMSD 0.42 Å
- 1YAR chain H against the predicted model P28061: TM-score 0.99, RMSD 0.43 Å
- 1YAR chain H against the predicted model P28061: TM-score 0.99, RMSD 0.43 Å
- 3JRM chain H against the predicted model P28061: TM-score 0.99, RMSD 0.44 Å
- 3JRM chain H against the predicted model P28061: TM-score 0.99, RMSD 0.44 Å
- 3JTL chain H against the predicted model P28061: TM-score 0.99, RMSD 0.45 Å
- 3JTL chain H against the predicted model P28061: TM-score 0.99, RMSD 0.45 Å
Elsewhere
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