UniProt P28037
Cytosolic 10-formyltetrahydrofolate dehydrogenase (P28037)
Cytosolic 10-formyltetrahydrofolate dehydrogenase (UniProt P28037), EC 1.5.1.6: 11 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 19 pockets. Binding sites, druggability and experiment against…
- UniProt
- P28037
- Protein
- Cytosolic 10-formyltetrahydrofolate dehydrogenase
- EC
- 1.5.1.6
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 19 · 1 record with a druggable one
Structures
12 records of P28037 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1S3I | Crystal structure of the N terminal hydrolase domain of 10-formyltetrahydrofolate dehydrogenase | x-ray diffraction | A | — | — |
| 1S3I | Crystal structure of the N terminal hydrolase domain of 10- formyltetrahydrofolate dehydrogenase | x-ray diffraction | A | — | — |
| 4GNZ | Crystal structure of the c707s mutant of c-terminal domain of 10'formyltetrahydrofolate… | x-ray diffraction | A, B, C, D | — | — |
| 4GNZ | Crystal structure of the C707S mutant of C-terminal domain of 10'FORMYLTETRAHYDROFOLATE… | x-ray diffraction | A, B, C, D | — | — |
| 4GO0 | Crystal structure of the c707s mutant of c-terminal domain of 10'formyltetrahydrofolate… | x-ray diffraction | A, B, C, D | — | — |
| 4GO0 | Crystal structure of the C707S mutant of C-terminal domain of 10'FORMYLTETRAHYDROFOLATE… | x-ray diffraction | A, B, C, D | — | — |
| 4GO2 | Crystal structure of the c-terminal domain of 10'formyltetrahydrofolate dehydrogenase in complex… | x-ray diffraction | A, B, C, D | — | — |
| 4GO2 | Crystal structure of the C-terminal domain of 10'FORMYLTETRAHYDROFOLATE dehydrogenase in complex… | x-ray diffraction | A, B, C, D | — | — |
| 7RLT | Structure of ligand-free ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) | electron microscopy | A, C, B, D | PNS | — |
| 7RLU | Structure of ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP | electron microscopy | A, B, D, C | NAP, PNS | 19 (best 0.87) |
| 7RLU | Structure of ALDH1L1 (10-formyltetrahydrofolate dehydrogenase) in complex with NADP | electron microscopy | A, B, D, C | NAP, PNS | — |
| P28037 | AlphaFold monomer V2.0 prediction for cytosolic 10-formyltetrahydrofolate dehydrogenase (P28037) | predicted | A | — | — |
Ligands
Experiment against prediction
- 4GO2 chain C against the predicted model P28037: TM-score 1.00, RMSD 0.23 Å
- 4GO2 chain C against the predicted model P28037: TM-score 1.00, RMSD 0.23 Å
- 4GO2 chain B against the predicted model P28037: TM-score 1.00, RMSD 0.24 Å
- 4GO2 chain B against the predicted model P28037: TM-score 1.00, RMSD 0.24 Å
- 4GO2 chain D against the predicted model P28037: TM-score 1.00, RMSD 0.25 Å
- 4GO2 chain D against the predicted model P28037: TM-score 1.00, RMSD 0.25 Å
- 4GO2 chain A against the predicted model P28037: TM-score 1.00, RMSD 0.25 Å
- 4GO2 chain A against the predicted model P28037: TM-score 1.00, RMSD 0.25 Å
- 4GNZ chain C against the predicted model P28037: TM-score 1.00, RMSD 0.27 Å
- 4GNZ chain C against the predicted model P28037: TM-score 1.00, RMSD 0.27 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.